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溶剂替换法制备β-胡萝卜素纳米粒子与稳定性

, PP. 112-115

Keywords: β-胡萝卜素,纳米粒子,粒径,分布,溶剂替换,稳定性

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Abstract:

采用溶剂替换法制备β-胡萝卜素纳米粒子,通过考察4种乳化剂对制备纳米粒子粒径及分布的影响和测定贮藏过程中粒子粒径和β-胡萝卜素含量变化,研究了其稳定性。试验结果表明:以酪蛋白钠为乳化剂制备的β-胡萝卜素纳米粒子粒径大于以Tween20、蔗糖脂肪酸酯和月桂酸十甘油酯为乳化剂制备的纳米粒子;向蔗糖脂肪酸酯中添加酪蛋白钠,以此混合物作为乳化剂可以制备平均粒径小于50nm的β-胡萝卜素纳米粒子;贮藏过程中,所有乳化剂制备的β-胡萝卜素纳米粒子粒径均保持较好的稳定性,β-胡萝卜素含量随着贮藏时间延长而减小,特别是在Tween20为乳化剂制备的纳米粒子中降解最为明显。

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