唐彬秩, 秦豪杰, 傅强, 等. 重组腺相关病毒:很有潜力的基因治疗载体[J]. 生物化学与生物物理进展, 2006, 33(8): 711-718. Tang Binzhi, Qing Haojie, Fu Qiang, et al. rAAV: a promising vehicle for gene therapy[J]. Progress in Biochemistry and Biophysics, 2006, 33 (8): 711-718.
[2]
Merten O-W, Al-Rubeai M. Viral vectors for gene therapy: Methods and protocols[M]. New York: Humana Press, 2011.
[3]
高凯, 王军志. 不同血清型腺相关病毒载体组织表达差异的研究进展 [J]. 中国肿瘤生物治疗杂志, 2007, 14(4): 388-392. Gao Kai, Wang Junzhi. Expression of different serotypes of adenoassociated virus vectors: anupdate[J]. Chinese Journal of Cancer Biotherapy, 2007, 14(4): 388-392.
[4]
Liu Y L, Wagner K, Robinson N, et al. Optimized production of hightiter recombinant adeno-associated virus in roller bottles[J]. BioTechniques, 2003, 34(1): 184-189.
[5]
Green M R, Sambrook J. Molecular cloning: a laboratory manual[M]. New York: Cold Spring Harbor Laboratory Press, 2012.
[6]
吴小兵, 董小岩, 伍志坚, 等. 一种快速高效分离和纯化重组腺病毒伴随病毒载体的方法[J]. 科学通报, 2000, 45(19): 2071-2075. Wu Xiaobing, Dong Xiaoyan, Wu Zhijian, et al. A rapid and effective method of separation and purification for recombinant adeno-associated virus[J]. Chinese Science Bulletin, 2000, 45(19): 2071-2075.
[7]
刁勇, 马健, 李欣燕, 等. 表达血管抑制因子的腺相关病毒载体的构建及其体内外活性[J]. 生物工程学报, 2008, 24(11): 1949-1954. Diao Yong, Ma Jian, Li Xinyan, et al. Construction and activity of recombinant adeno-associated virus Expressing Vasostatin[J]. Chinese Journal of Biotechnology, 2008, 24(11): 1949-1954.
[8]
Grimm D, Kern A, Rittner K, et al. Novel tools for production and purification of recombinant adenoassociated virus vectors[J]. Human Gene Therapy, 1998, 9(18): 2745-2760.
[9]
Xiao X, Li J, Samulski R J. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus[J]. Journal of Virology, 1998, 72(3): 2224-2232.
[10]
Grieger J C, Choi V W, Samulski R J. Production and characterization of adeno-associated viral vectors[J]. Nature Protocols, 2006, 1(3): 1412-1428.
[11]
马宏, 刘彦信, 刘士廉, 等. 腺相关病毒介导的肿瘤坏死因子相关细胞凋亡诱导配体的表达及其体外抗肿瘤活性的研究[J]. 中华医学杂志, 2004, 84(19): 1635-1641. Ma Hong, Liu Yanxin, Liu Shilian, et al. Expression of TRAIL114-281 mediated by adeno-associated virus and its tumoricidal activity [J]. National Medical Journal of China, 2004, 84(19): 1635-1641.
[12]
Zhang T, Hu J, Ding W, et al. Doxorubicin augments rAAV-2 transduction in rat neuronal cells[J]. Neurochemistry International, 2009, 55(7): 521-528.
[13]
赵丽琴, 席斌, 彭华松. 腺相关病毒( AAV) 载体研究进展[J]. 生物技术进展, 2012, 2(2): 110-115. Zhao Liqin, Xi Bin, Peng Huasong. Advances on Research of Adenoassociated Virus Vectors[J]. Current Biotechnology, 2012, 2(2): 110-115.
[14]
DecressacM,MattssonB,LundbladM,etal.Progressiveneurodegenerative and behavioural changes induced by AAV-mediated overexpression of alpha-synuclein in midbrain dopamine neurons[J]. Neurobiology of Disease, 2012, 45(3): 939-953.
[15]
Mulcahy P, O'doherty A, Paucard A, et al. The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's diseaseassociated pesticide, rotenone, in rats[J]. Behavioural Brain Research, 2013, 243: 6-15.
[16]
Oliveras-Salva M, Macchi F, Coessens V, et al. Alpha-synucleininduced neurodegeneration is exacerbated in PINK1 knockout mice[J]. Neurobiology of Aging, 2014, 35(11): 2625-2636.
