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科技导报  2015 

龙血竭对Lewis肺癌小鼠放疗模型的辅助治疗效果

DOI: 10.3981/j.issn.1000-7857.2015.18.011, PP. 68-71

Keywords: 龙血竭,放疗,Lewis,肺癌小鼠,放疗辅助用药

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Abstract:

龙血竭具有一定的防辐射作用。通过在C57/BL小鼠右前腋窝皮下注射Lewis肺癌细胞,对小鼠进行4Gy全身一次性γ辐射建立Lewis肺癌小鼠放疗模型,并给予小鼠龙血竭,进行肿瘤生长、肿瘤转移和血象变化检测,研究了龙血竭对Lewis肺癌小鼠放疗模型的血象及肿瘤生长的辅助治疗效果。实验发现,龙血竭不会促进放疗Lewis肺癌小鼠的肿瘤生长和转移,并能够有效保护放疗Lewis肺癌小鼠的血小板。研究表明,龙血竭应用于肿瘤的放射治疗可以对辐射引起机体的血象损伤起到保护作用。

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