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科技导报  2015 

BSD2000深部热疗联合化疗治疗局部晚期胰腺癌患者的

DOI: 10.3981/j.issn.1000-7857.2015.12.012, PP. 72-76

Keywords: 胰腺癌,化疗,热疗,疼痛和生活质量

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Abstract:

为探讨BSD2000深部相控阵聚能热疗系统(BSD2000)联合化疗治疗局部晚期胰腺癌患者的近期疗效、疼痛及生活质量改善和不良反应,收集2009年10月至2014年10月在北京医院肿瘤内科确诊的30例局部晚期胰腺癌患者,给予化疗同时联合局部热疗的治疗方法(联合组),同时选取同期住院治疗30例局部晚期胰腺癌患者,仅给予单纯化疗作为对照组(化疗组),评估两组治疗效果及不良反应,观察两组在生活质量及疼痛改善方面有无差异。结果显示,联合组和化疗组的有效率和疾病控制率分别为10%、6.7%和83%、76%,两组相比无统计学差异(P>0.05),联合组治疗后疼痛及生活质量的改善均明显优于化疗组,差异具有统计学意义(P<0.05)。骨髓抑制和胃肠道反应是最常见的不良反应,两组相比发生率无明显差异(P>0.05),热疗与化疗联合并不增加毒副反应,两组均无严重不良反应发生。结果表明,在化疗基础上联合热疗可以明显减轻疼痛症状,提高患者的生活质量,且治疗简单,副作用较小,临床可操作性好,值得推广。

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