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牦牛与犏牛联会复合体蛋白b-FKBP6基因的表达特征分析

DOI: 10.7685/j.issn.1000-2030.2013.05.022, PP. 129-132

Keywords: 牦牛,犏牛,b-FKBP6基因,表达特征

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Abstract:

联会复合体蛋白FKBP6是哺乳动物精子发生减数分裂联会复合体形成必需的。采用RT-PCR和荧光定量PCR技术对牦牛和犏牛b-FKBP6基因的组织表达特征,以及牦牛与犏牛睾丸组织中b-FKBP6mRNA表达水平进行了分析。结果显示b-FKBP6基因在牦牛、犏牛睾丸和卵巢组织中特异表达,且牦牛睾丸组织中b-FKBP6mRNA表达水平极显著高于犏牛(P<0.01)。结合犏牛精子发生减数分裂联会复合体形成障碍表型,推测睾丸组织b-FKBP6mRNA表达水平可能与犏牛雄性不育有一定的关系。

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