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基于边缘链码信息的黏连细胞分割算法

Keywords: 图像处理,图像分割,细胞黏连,链码和,链码差

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Abstract:

介绍了一种基于边缘链码信息的黏连细胞自动分割算法.该算法对弱对比度的细胞图像预处理;对二值化图像进行链码跟踪,并计算边缘各点的链码和、链码差、等效周长、弧弦比等特征参数;利用特征参数判断边缘光滑段、边缘角点;对真实分割角点进行线性插值最终实现黏连细胞的分割.将该算法应用于2组细胞图像序列共120帧图像的分割中,不仅解决了黏连细胞的分割难题,而且能够准确进行细胞凹陷的修补和细胞图像的简单计数.统计结果表明,相比于阈值法和先验模型法,该算法的分割成功帧占整个序列的百分比提高40%~60%.

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