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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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原子转移自由基聚合在生物传感中的应用
DOI: 10.3724/SP.J.1096.2012.20531, PP. 1797-1802
Keywords: 原子转移自由基聚合,信号放大,生物传感,脱氧核糖核酸(DNA),蛋白质,评述
Abstract:
原子转移自由基聚合(ATRP)是一种新颖的信号放大方法。在聚合过程中,成百上千个单体分子聚集形成长链聚合物,聚合物的侧链可以修饰丰富的功能基团,可与电化学或光学活性物质发生键合反应,从而显著增加单元生物分子识别反应信号分子的负载量,提高了检测灵敏度,实现了生物分子检测的信号放大。本文综述了ATRP的反应机理及其近年来在生物传感中的应用,并展望了其发展前景。
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