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分析化学  2015 

毛细管电泳法在酶抑制剂筛选中的应用

DOI: 10.11895/j.issn.0253-3820.141081, PP. 775-782

Keywords: 毛细管电泳,酶抑制剂,柱前酶反应,在柱酶反应,综述

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Abstract:

毛细管电泳法以其分离效率高、耗时短、样品用量少、灵敏度高以及易于实现自动化等诸多特点,在筛选酶抑制剂研究中有着不可替代的优势。本文综述了毛细管电泳法在酶抑制剂筛选中的应用。主要介绍了应用最广泛的离线分析(Off-lineassay)和在线分析(In-lineassay),即柱前酶反应(Pre-capillaryenzymereaction)和在柱酶分析(In-capillaryenzymereaction)。并对该领域的未来发展进行了展望。

 References

[1]  1 da Silva J I, de Moraes M C, Vieira L C, Correa A G, Cass Q B, Cardoso C L. J. Pharm. Biomed. Anal., 2013, 73: 44-52
[2]  2 Jiang T F, Liang T T, Wang Y H, Zhang W H, Lv Z H. J. Pharm. Biomed. Anal., 2013, 84: 36-40
[3]  3 Brühlmann C, Marston A, Hostettmann K, Carrupt P A, Testa B. Chem. Biodivers., 2004, 1(6): 819-829
[4]  4 MI Xuan, ZHU Ruo-Hua, ZHANG Xin-Yue. Chemistry Online, 2010, 09: 778-786米 璇, 朱若华, 张馨月. 化学通报, 2010, 09: 778-786
[5]  5 Zhang J, Hoogmartens J, van Schepdael A. Electrophoresis, 2008, 29(17): 3694-3700
[6]  6 Hempel G. Electrophoresis, 2000, 21(4): 691-698
[7]  7 Iqbal J, Levesque S A, Sevigny J, Muller C E. Electrophoresis, 2008, 29(17): 3685-3693
[8]  8 van Dyck S, Vissers S, van Schepdael A, Hoogmartens J. J. Chromatogr. A, 2003, 986(2): 303-311
[9]  9 Yeniceli D, Deng X, Adams E, Dogrukol-Ak D, van Schepdael A. Electrophoresis, 2013, 34(3): 463-470
[10]  10 Abromeit H, Kannan S, Sippl W, Scriba G K. Electrophoresis, 2012, 33(11): 1652-1659
[11]  11 XIN Zhin-Hong, MA Hai-Le, WU Shou-Yi, DAI Chun-Hua. Acta. Pharm. Suec., 2003, 38(11): 843-845辛志宏, 马海乐, 吴守一, 代春华. 药学学报, 2003, 38(11): 843-845
[12]  12 LI Na, ZHANG Xin-Yue, ZHU Ruo-Hua. J. Anal. Sci., 2008, 24(6): 631-635栗 娜, 张馨月, 朱若华. 分析科学学报, 2008, 24(6): 631-635
[13]  13 JIA Rui, LI Na, ZHU Ruo-Hua. Chinese Journal of Chromatography, 2007, 27(02): 189-192贾 蕊,栗 娜,朱若华. 色谱, 2007, 27(02): 189-192
[14]  14 ZHONG Lei,ZHANG Ya-Xi, WANG Nan, JIANG Ting-Fu, LV Zhi-Hua. Chinese J. Mar. Drugs, 2014, 33(06): 47-51种 蕾, 张亚西, 王 楠, 姜廷褔, 吕志华. 中国海洋药物, 2014, 33(06): 47-51
[15]  15 Iqbal J, Burbiel J C, Muller C E. Electrophoresis, 2006, 27(12): 2505-2517
[16]  16 Chen W, Mou K, Xu B, Ling X, Cui J, Xu P. Anal. Biochem., 2009, 394(1): 62-67
[17]  17 LI Bing, LV Xue-Fei, QING Hong, DENG Yu-Lin. Chinese J. Anal. Chem., 2012, 40(9): 1336-1340李 冰, 吕雪飞, 庆 宏, 邓玉林. 分析化学, 2012, 40(9): 1336-1340
[18]  18 Bryant S K, Waldrop G L, Gilman S D. Anal. Biochem., 2013, 437(1): 32-38
[19]  19 Iqbal S, Nisar-ur-R, Iqbal J. Anal. Biochem., 2014, 444: 16-21
[20]  20 Malina A, Bryant S K, Chang S H, Waldrop G L, Gilman S D. Anal. Biochem., 2014, 447: 1-5
[21]  21 Urban P L, Goodall D M, Bergstr？m E T, Bruce N C. Electrophoresis, 2007, 28(12): 1926-1936
[22]  22 Fan Y, Scriba G K. J. Pharm. Biomed. Anal., 2010, 53(5): 1076-1090
[23]  23 Bao J, Regnier F E. J. Chromatogr. A, 1992, 608(1): 217-224
[24]  24 Harmon B J, Leesong I, Regnier F E. J. Chromatogr. A, 1996, 726: 193-204
[25]  25 Dyck SV,van Schepdael A, Hoogmartens J. Electrophoresis, 2001, 22(7): 1436-1442
[26]  26 Guo L P, Jiang T F, Lv Z H, Wang Y H. J. Pharm. Biomed. Anal., 2010, 53(5): 1250-1253
[27]  27 Krylova S M, Okhonin V, Krylov S N. J. Sep. Sci., 2009, 32(5-6): 742-756
[28]  28 Zhao H, Chen Z. J. Sep. Sci., 2013, 36(16): 2691-2697
[29]  29 Nehmé H, Nehmé R, Lafite P, Routier S, Morin P. J. Sep. Sci., 2013, 36(13): 2151-2157
[30]  30 Sanders B D, Slotcavage R L, Scheerbaum D L, Kochansky C J, Strein T G. Anal. Chem., 2005, 77(8): 2332-2337
[31]  31 Hai X, Yang B F, Schepdael A V. Electrophoresis, 2012, 33(1): 211-227
[32]  32 Taga A, Honda S. J. Chromatogr. A, 1996, 742(1-2): 243-250
[33]  33 Iqbal J, Vollmayer P, Braun N, Zimmermann H, Muller C E. Purinergic Signalling., 2005, 1(4): 349-358
[34]  34 Wang T, Zhang Q, Zhang Y, Kang J. J. Chromatogr. A, 2014, 1337: 188-193
[35]  35 Nehmé H, Nehmé R, Lafite P, Routier S, Morin P. Anal. Chim. Acta, 2012, 722: 127-135
[36]  36 Iqbal J, Iqbal S, Müller C E. Analyst, 2013, 138(11): 3104-3116
[37]  37 JI Xiao-Wen, ZHAO Shu-Lin, LIN Pin-Tan, YE Fang-Gui, HU Kun. Chinese J. Anal. Chem., 2009, 37(A02): 128冀晓雯, 赵书林, 林娉毯, 叶芳贵, 胡 坤. 分析化学, 2009, 37(A02): 128
[38]  38 Iqbal J. Anal. Biochem., 2011, 414(2): 226-231
[39]  39 Tang Z M, Kang J W. Anal. Chem., 2006, 78(8): 2514-2520
[40]  40 Yin Z, Zhao W,Tian M, Zhang Q, Guo L, Yang L. Analyst., 2014, 139(8): 1973-1979
[41]  41 Zhao S, Ji X, Lin P, Liu Y M. Anal. Biochem., 2011, 411(1): 88-93
[42]  42 Lin P, Zhao S, Lu X, Ye F, Wang H. J. Sep. Sci., 2013, 36(15): 2538-2543
[43]  43 LIN Pin-Tan, LU Jun-Yu, YE Gui-Fang, ZHAO Shu-Lin. National Biomedical Chromatography and Related Techniques of Academic Exchanges (2012) the Conference Brochure, 2012 林娉毯, 陆俊宇, 叶芳贵, 赵书林. 全国生物医药色谱及相关技术学术交流会(2012)会议手册, 2012
[44]  44 Zhang A, Ye F, Lu J, Zhao S. Food Chem., 2013, 141(3): 1854-1859
[45]  45 SHEN Gang-Yi, YU Wan-Ting, ZHANG Ai-Qin, LIU Mei-Rong, WANG Ning. Chinese J. Anal. Lab., 2014, 33(4): 392-394申刚义, 于婉婷, 张爱芹, 刘美蓉, 王 宁. 分析试验室, 2014, 33(4): 392-394
[46]  46 Min W, Cui S, Wang W, Chen J, Hu Z. Anal. Biochem., 2013, 438(1): 32-38
[47]  47 Wang S, Su P, Yang Y. Anal. Biochem., 2012, 427(2): 139-143
[48]  48 Zhao H, Chen Z. J. Chromatogr. A, 2014, 1340: 139-145
[49]  49 Liu L, Zhang B, Zhang Q, Shi Y, Guo L, Yang L. J. Chromatogr. A, 2014, 1352: 80-86
[50]  50 Mu X, Qiao J, Qi L, Liu Y, Ma H. ACS Appl. Mater. Interfaces, 2014, 6(15): 12979-12987
[51]  51 Wang S, Su P, Huang J, Wu J, Yang Y. J. Mater. Chem. B, 2013, 1(12): 1749-1754
[52]  52 Alex D, Mathew A, Sukumaran R K. Bioresour. Technol., 2014, 167: 547-550
[53]  53 Okhonin V, Liu X, Krylov S N. Anal. Chem., 2005, 77(18): 5925-5929
[54]  54 Nehmé H, Nehmé R, Lafite P, Routier S, Morin P. J. Chromatogr. A, 2013, 1314: 298-305
[55]  55 Nehmé R, Nehmé H, Roux G, Destandau E, Claude B, Morin P. J. Chromatogr. A, 2013, 1318: 257-264

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