全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
电化学  2006 

旋转玻碳电极上二茂铁的电化学阻抗行为及其与DNA的相互作用

, PP. 170-176

Keywords: 二茂铁,DNA,旋转圆盘电极,电化学阻抗谱

Full-Text   Cite this paper   Add to My Lib

Abstract:

应用旋转圆盘电极和电化学阻抗法研究了二茂铁在Tris-NaCl(pH=7.2)缓冲溶液中于旋转玻碳电极上的电化学阻抗行为及其与DNA的相互作用.结果表明,二茂铁于旋转电极的伏安曲线呈现明显的极限电流平阶,而其交流阻抗谱则出现两个电容弧.二茂铁与DNA的作用,若受扩散过程控制则其极限扩散电流随DNA浓度增大而减小,而在电化学控制过程中则表现为电化学反应电阻随DNA浓度增大而增大.根据旋转圆盘电极和电化学阻抗谱测试,表明由这两种方法数据拟合求得的二茂铁条件电位速率常数能够很好地相互吻合,但如存在DNA时,则其条件电位速率常数有一定程度的减小.

References

[1]  Ibrah im M S,Shehatta I S,A l-Nayeli A A.Voltamm et-ric stud ies of the interaction of lum azine w ith cyc lodex-trins and DNA[J].J.Pharm.B iom ed.Anal.,2002,28:217~225.
[2]  Tang P ing(唐平),Zeng Bai-zhao(曾百肇).E lecro-chem ical behavior of ep inephrine at deoxyribonuc le ic aidmod ified gold electrodes and influence of lead iron[J].Ch inese J.Anal.Chem.,2003,31(6):641~645.
[3]  Zhou Jian-zhang(周剑章),W u L ing-ling(吴玲玲),Dong L i-q in(董丽琴),et al.Immob ilization of longstrand DNA onto gold surface and electrochem ical labe-ling of hybrid ization ofDNA[J].E lectrochem.,2001,7(3):276~280.
[4]  LüJia-gen(吕家根),Zhang Zhu-jun(章竹君),ZhengHu-zh i(郑鹄志).In vivo determ ination of copper m e-tabolism in rabb it serum based on a new electrochem ilu-m inescence[J].Acta Ch im.S in ica,2002,60(7):1274~1278.
[5]  Pang D W,Abr a H D.M icrom ethod for the investiga-tion of the interactions between DNA and redox-activemolecu les[J].J.Anal.Chem.,1998,70(15):3162~3169.
[6]  L i Hong(李红),Jiang X iong(蒋雄),W ang Le i(王雷),et al.E lectrochem ical stud ies on the interactionsof the comp lex of Co(phen)2TATP3+w ith DNA at rota-ting Au-Au electrode[J].Chem.J.Ch inese Un iversi-ties,2000,212(7):995~998.
[7]  B rett C M A,O live ira B A M,Serrano S H P.An EISstudy ofDNA-mod ified electrodes[J].E lectroch im.Ac-ta,1999,44:4233~4239.
[8]  Popova L V,Bab in V N,Belousov Y A,et al.Antitu-mor effects of b inuc lear ferrocene derivatives[J].App l.O rganom et.Chem.,1993,7:85~94.
[9]  CarterM T,RodriguezM,Bard A J.Voltamm etric stud-ies of interaction of m etal chelates w ith DNA.2.Tris-chelated comp lexes of cobalt(Ⅲ)and iron(Ⅱ)w ith 1,10-phenanthroline and 2,2-′b ipyrid ine[J].J.Am.Chem.Soc.,1989,111(24):8901~8911.
[10]  Bard A J,Fau lkner L R.E lectrochem icalM ethods:Fun-dam entals and App lication[M],New York:JohnW ileyand Sons,1980.92~292.
[11]  Randriam ahazaka H,Noёl V,Chevrot C.Fractal d i-m ension of the active zone for a p-doped poly(3,4-ethyl-ened ioxyth iophene)mod ified electrode towards a ferro-cene probe[J].J.E lectroanal.Chem.,2003,556:35~42.
[12]  S ilvestri A,Barone G,Ru isi G.,et al.The interactionof native DNA w ith iron(III)-N,N′-ethylene-b is(salicyli-dene im inato)-chloride[J].J.Inorg.B iochem.,2004,98(4):589~594.
[13]  Jiang Cai-wu(蒋才武).Synthesis,characterization andDNA b ind ing stud ies of novel asymm etric tridentate poly-pyrid ine ligand and the ir heteroleptic ruthen ium(Ⅱ)comp lexes[J].Acta Ch im.S in ica,2004,62(7):692~696.
[14]  Zhou Y L,L i Y Z.Stud ies of the interaction between po-ly(d iallyld im ethyl ammon ium chloride)and DNA byspectroscop ic m ethods[J].Colloids and Surfaces A:Physicochem.Eng.Aspects,2004,233:129~135.
[15]  Yang Gong-jun(杨功俊),Xu Jing-juan(徐静娟),ChenHong-yuan(陈洪渊).Stud ies on the interaction betweencatecholam ine derivatives and DNA by m eans of spectro-scop ic and voltamm etric m ethods[J].Chem.J.Ch ineseUn iversities,2004,25(7):1235~1239.
[16]  W ang Shu-ling(王树玲),Yu Jun-sheng(于俊生).SERS stud ies on the interaction of berberine w ith ctDNA[J].Chem.J.Ch inese Un iversities,2002,23(9):1676~1679.
[17]  Palan isamy U M,M allayan P.DNA b ind ing and c leavageactivity of[Ru(NH3)4(d iim ine)]C l2comp lexes[J].Inorg.Ch im.Acta,2004,357:901~912.
[18]  Jiang C W.Ch iral d iruthen ium(II)comp lexes contain inga mod ified 4,4′-b ipyrid ine bridging ligand:syntheses,characterization and DNA b ind ing[J].Inorg.Ch im.Ac-ta,2004,357:3403~3406.
[19]  Fazlu lH,Jun Q Y,Hassan D,et al.Stud ies on activi-ties,cell uptake and DNA b ind ing of fourtrans-p lanara-m inep latinum(II)comp lexes of the form:trans-PtL(NH3)C l2,where L=2-hydroxypyrid ine,im idazole,3-hydroxypyrid ine and im idazo(1,2-α)pyrid ine[J].J.Inorg.B iochem.,2004,98:1261~1270.
[20]  Pérez-CabréM,Cervantes G,Moreno V,et al.Pd(II)and Pt(II)comp lexes w ith arom atic d iam ines:study ofthe ir interaction w ith DNA[J].J.Inorg.B iochem.,2004,98:510~521.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133