全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

胸腹腔镜联合食管癌根治术与传统食管癌根治术同期临床对照研究

, PP. 2142-2144

Keywords: 食管肿瘤,腔镜手术,开放手术,临床疗效

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨胸腹腔镜联合下食管癌根治术治疗食管癌的临床疗效。方法回顾性分析2012年10月至2014年6月在本科因食管癌行食管癌根治术患者108例。51例患者行胸腹腔镜食管癌根治术(minimallyinvasiveesophagectomy,MIE),57例患者行传统开放食管癌根治术(openesophagectomy,OE)。从手术结局、肿瘤学结局、围术期并发症三方面评估两种手术的临床疗效。结果两组患者一般资料比较无显著性差异(P>0.05)。MIE组与OE组手术时间,术中输血患者比例无明显差异(P>0.05)。MIE组和OE组比较,术中出血量[(150.5±30.4)vs(215.5±40.4)mL],术中平均输液量(2.2vs3.1L),术后ICU监护时间(1vs2d),禁食时间(6vs8d),术后住院时间(8vs10d)有显著性差异(P<0.05)。两组患者平均淋巴结切除数目、切缘阳性率无显著性差异(P>0.05),肺部并发症发生率MIE组2例(3.9%),明显少于OE组25(43.8%)。结论胸腹腔镜联合下食管癌根治术不仅可以达到与开放手术相同的肿瘤切除效果,且在减少术后住院时间、术中出血量及减少术后肺部并发症方面较开放手术更有优势。

References

[1]  Jemal A, Bray F, Center M M, et al. Global cancer statistics[J]. CA Cancer J Clin, 2011, 61(2): 69-90. [2]Pennathur A, Zhang J, Chen H, et al. The “best operation” for esophageal cancer?[J]. Ann Thorac Surg, 2010, 89(6): S2163-S2167. [3]Mamidanna R, Bottle A, Aylin P, et al. Short-term outcomes following open versus minimally invasive esophagectomy for cancer in England: a population-based national study[J]. Ann Surg, 2012, 255(2): ?197-203?. [4]Parameswaran R, Titcomb D R, Blencowe N S, et al. Assessment and comparison of recovery after open and minimally invasive esophagectomy for cancer: an exploratory study in two centers[J]. Ann Surg, 2013, 20(6): 1970-1977. [5]Gao Y, Wang Y, Chen L, et al. Comparison of open three-field and minimally-invasive esophagectomy for esophageal cancer[J]. Interact Cardiovasc Thorac Surg, 2011, 12(3): 366-369. [6]Berger A C, Bloomenthal A, Weksler B, et al. Oncologic efficacy is not compromised, and may be improved with minimally invasive esophagectomy[J]. J Am Coll Surg, 2011, 212(4): 560-568. [7]Briez N, Piessen G, Bonnetain F, et al. Open versus laparoscopically-assisted oesophagectomy for cancer: a multicentre randomised controlled phase Ⅲ trial - the MIRO trial[J]. BMC Cancer, 2011, 11: 310. [8]Sihag S, Wright C D, Wain J C, et al. Comparison of perioperative outcomes following open versus minimally invasive Ivor Lewis oesophagectomy at a single, high-volume centre[J]. Eur J Cardiothorac Surg, 2012, 42(3): 430-437. [9]王晓骏, 张铸, 孙清超. 胸腹腔镜联合下食管癌切除术与开放手术疗效对比的Meta分析[J]. 世界华人消化杂志, 2014, 22(3): 375-382. [10]Rosati R, Fumagalli U, Elmore U, et al. Long-term results of minimally invasive surgery for symptomatic epiphrenic diverticulum[J]. Am J Surg, 2011, 201(1): 132-135. [11]Levy R M, Wizorek J, Shende M, et al. Laparoscopic and thoracoscopic esophagectomy[J]. Adv Surg, 2010, 44: 101-116. [12]Nafteux P, Moons J, Coosemans W, et al. Minimally invasive oesophagectomy: a valuable alternative to open oesophagectomy for the treatment of early oesophageal and gastro-oesophageal junction carcinoma[J]. Eur J Cardiothorac Surg, 2011, 40(6): 1455-1464. [13]Biere S S, Cuesta M A, van-der-Peet D L. Minimally invasive versus open esophagectomy for cancer: a systematic review and meta-analysis[J]. Minerva Chir, 2009, 64(2): 121-133. [14]Verhage R J, Hazebroek E J, Boone J, et al. Minimally invasive surgery compared to open procedures in esophagectomy for cancer: a systematic review of the literature[J]. Minerva Chir, 2009, 64(2): ?135-146?. [15]Biere S S, van-Berge-Henegouwen M I, Maas K W, et al. Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial[J]. Lancet, 2012, 379(9829): 1887-1892.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133