全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

窄带光谱成像技术联合放大内镜在咽喉部肿瘤诊断中的应用

, PP. 2504-2507

Keywords: NBI放大内镜,咽喉部肿瘤,诊断

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨窄带光谱成像技术(narrowbandimaging,NBI)联合放大内镜检查在咽喉部肿瘤诊断中的应用价值。方法选取2011年7月至2014年6月我科胃镜中心的105000例患者进行胃镜检查,在胃镜检查前先常规用白光进行咽喉部的观察,然后再用NBI模式光对咽部进行观察,发现病变及时送病理检查。结果检出咽喉部肿瘤22例(0.021%),包括进展期鳞状细胞癌10例(0.010%)和早期癌(包括高级别上皮内瘤变及原位癌)12例(0.011%)。其中在进展期鳞状细胞癌的诊断中,NBI内镜(9例)和白光内镜(10例),两组无显著差异(P>0.05);在早期癌的诊断中,NBI内镜(12例)和白光内镜(1例),两组有显著差异(P<0.01)。咽部癌并食道癌者共占45.45%(10/22),咽部癌合并直肠癌1例。结论NBI放大内镜检查前对咽喉部早期癌的检出率优于白光内镜,但是对于进展期咽喉癌的诊断,NBI内镜和白光内镜无差异。在检查中应特别注意咽部癌和食道癌同时存在的情况。

References

[1]  倪晓光, 贺舜, 高黎, 等. 窄带成像内镜在喉咽癌早期诊断中的应用[J]. 中国耳鼻咽喉头颈外科, 2009, 16(10): 550-554. [2]Vohen J. 消化内镜: 高清内镜和窄带成像综合图谱[M]. 黄志刚, 译. 北京: 人民卫生出版社, 2012: 27-39. [3]郑宏良, 张才云. 窄带成像技术在喉咽癌诊断中的应用[J]. 中国医学文摘: 耳鼻咽喉科学, 2011, 26(4): 197-199. [4]施清圆, 李文峰, 李刚, 等. 晚期喉咽癌术后综合治疗的疗效及生存分析[J]. 临床耳鼻咽喉头颈外科杂志, 2013, 24(4): 206-209. [5]Nonaka S, Saito Y. Endoscopic diagnosis of pharyngeal carcinoma by NBI[J]. Endoscopy, 2008, 40(4): 347-351. [6]Muto M, Horimatsu T, Ezoe Y,et al. Narrow-band imaging of the gastrointestinal tract[J]. J Gastroenterol, 2009, 44(1): 13-25. [7]Muto M, Nakane M, Katada C,et al. Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites[J]. Cancer, 2004, 101(6): 1375-1381. [8]Parkin D M, Pisani P, Ferlay J. Estimates of the worldwide incedence of 25 major cancers in 1990[J]. Int J Cancer, 1999, 80(6): 827-841. [9]Yoshimura N, Goda K, Tajiri H,et al. Diagnostic utility of narrow-band imaging endoscopy for pharyngeal superficial carcinoma[J]. World J Gastroenterol, 2011, 17(45): 4999-5006. [10]Muto M, Katada C, Sano Y,et al. Narrow band imaging: a new diagnostic approach to visualize angiogenesis in superficial neoplasm[J]. Clin Gastroenterol Hepatol, 2005, 3(7 Suppl 1): S16-S20. [11]Nonaka S, Saito Y, Oda I,et al. Narrow-band imaging endoscopy with magnification is useful for detecting metachronous superficial pharyngeal cancer in patients with esophageal squamous cell carcinoma[J]. J Gastroenterol Hepatol, 2010, 25(2): 264-269. [12]Muto M, Satake H, Yano T,et al. Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer[J]. Gastrointest Endosc, 2011, 74(3): 477-484. [13]McCaul J A, Cymerman J A, Hislop S,et al. LIHNCS? Lugol’s iodine in head and neck cancer surgery: a multicentre, randomised controlled trial assessing the effectiveness of Lugol’s iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma: study protocol for a randomised controlled trial[J]. Trials, 2013, 14: 310. [14]Saito M, Yamashita K, Tanuma T,et al. Pharyngeal cancer surveillance using narrow band imaging during conventional upper gastrointestinal endoscopy[J]. Digestion, 2013, 88(4): 229-234. [15]Saito Y, Ebihara Y, Ushiku T,et al. Negative human papillomavirus status and excessive alcohol consumption are significant risk factors for second primary malignancies in Japanese patients with oropharyngeal carcinoma[J]. Jpn J Clin Oncol, 2014, 44(6): 564-569.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133