Yin X F, Chen J, Mao W, et al. A selective aryl hydrocarbon receptor modulator 3,3'-Diindolylmethane inhibits gastric cancer cell growth[J]. J Exp Clin Cancer Res, 2012, 31: 46. [2]Watanabe M, Ishiwata T, Nishigai K, et al. Overexpression of keratinocyte growth factor in cancer cells and enterochromaffin cells in human colorectal cancer[J]. Pathol Int, 2000, 50(5): 363-372. [3]D'Amici S, Ceccarelli S, Vescarelli E, et al. TNFalpha modulates Fibroblast Growth Factor Receptor 2 gene expression through the pRB/E2F1 pathway: identification of a non-canonical E2F binding motif[J]. PLoS One, 2013, 8(4): e61491. [4]Frauenstein K, Sydlik U, Tigges J, et al. Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the? aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1[J]. Cell Death Differ, 2013, 20(10): 1425-1434. [5]Torres C, Perales S, Alejandre M J, et al. Serum cytokine profile in patients with pancreatic cancer[J]. Pancreas, 2014, 43(7): 1042-1049. [6]Kesinger J W, Mehta M, Lerner M R, et al. Oncolytic potential of a novel KGFR tyrosine kinase inhibitor using a KGFR-selective breast cancer xenograft model[J]. Anticancer Res, 2015, 35(1): 47-52. [7]Lin P, Chang H, Tsai W T, et al. Overexpression of aryl hydrocarbon receptor in human lung carcinomas[J]. Toxicol Pathol, 2003, 31(1): 22-30. [8]Di-Meglio P, Duarte J H, Ahlfors H, et al. Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions[J]. Immunity, 2014, 40(6): 989-1001. [9]Ji T, Xu C, Sun L, et al. Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis[J]. Dig Dis Sci, 2015, 60(7):1958-1966. [10]Brinkman A M, Wu J, Ersland K, et al. Estrogen receptor alpha and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells[J]. BMC Cancer, 2014, 14: 344. [11]Chang C C, Sue Y M, Yang N J, et al. 3-Methylcholanthrene, an AhR agonist, caused cell-cycle arrest by histone deacetylation through a RhoA-dependent recruitment of HDAC1 and pRb2 to E2F1 complex[J]. PLoS One, 2014, 9(3): e92793. [12]Xu G, Liu J, Yoshimoto K, et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces expression of p27(kip1) and? FoxO3a in female rat cerebral cortex and PC12 cells[J]. Toxicol Lett, 2014, 226(3): 294-302. [13]Murray I A, Flaveny C A, DiNatale B C, et al. Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone[J]. J Pharmacol Exp Ther, 2010, 332(1): 135-144. [14]Choi E Y, Lee H, Dingle R W, et al. Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor[J]. Mol Pharmacol, 2012, 81(1): 3-11. [15]Gadupudi G, Gourronc F A, Ludewig G, et al. PCB126 inhibits adipogenesis of human preadipocytes[J]. Toxicol ?In Vitro?, 2015, 29(1): 132-141.