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早期使用血管加压素治疗感染性休克的临床研究

, PP. 1596-1598

Keywords: 感染性休克血管加压素去甲肾上腺素

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Abstract:

目的探讨早期应用血管加压素对去甲肾上腺素使用的剂量和持续时间以及相关的不良事件发生率的影响。方法选取去甲肾上腺素治疗6h内开始血管加压素治疗者为早期治疗组(n=38),去甲肾上腺素治疗开始6h后开始血管加压素治疗者为晚期治疗组(n=42),比较两组患者儿茶酚胺使用时间,ICU监护时间,住院时间,病死率,新发心率失常发生率等。结果两组患者中基础血流动力学等改变无统计学差异,平均ICU监护时间及住院时间两组间比较无显著性差异。死亡率无显著性差异。儿茶酚胺使用时间两组间无显著差异,但9例新发心率失常发生率早期为34.2%,晚期组为57.1%,两组间比较有显著性差异(P<0.05)。结论早期使用血管加压素可降低新发心律失常的发生率。

References

[1]  Lam S W, Bauer S R, Guzman J A. Septic shock: the initial moments and beyond[J]. Cleve Clin J Med, 2013, 80(3): 175-184. [2]Hollenberg S M. Vasoactive drugs in circulatory shock[J]. Am J Respir Crit Care Med, 2011, 183(7): 847-855. [3]Rivers E P, Katranji M, Jaehne K A,et al. Early interventions in severe sepsis and septic shock: a review of the evidence one decade later[J]. Minerva Anestesiol, 2012, 78(6): 712-724. [4]Dellinger R P, Levy M M, Rhodes A,et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012[J]. Intensive Care Med, 2013, 39(2): 165-228. [5]Sadaka F, Juarez M, Naydenov S,et al. Fluid resuscitation in septic shock: the effect of increasing fluid balance on mortality[J]. J Intensive Care Med, 2014, 29(4): 213-217. [6]Dellinger R P, Levy M M, Rhodes A,et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012[J]. Crit Care Med, 2013, 41(2): 580-637. [7]Daley M J, Lat I, Mieure K D,et al. A comparison of initial monotherapy with norepinephrine versus vasopressin for resuscitation of septic shock[J]. Ann Pharmacother, 2013, 47(3): 301-310. [8]Russell J A. Bench-to-bedside review: vasopressin in the management of septic shock[J]. Crit Care, 2011, 15(4): 226. [9]De-Backer D, Biston P, Devriendt J,et al. Comparison of dopamine and norepinephrine in the treatment of shock[J]. N Engl J Med, 2010, 362(9): 779-789. [10]Russell J A, Walley K R, Singer J,et al. Vasopressin versus norepinephrine infusion in patients with septic shock[J]. N Engl J Med, 2008, 358(9): 877-887. [11]周飞虎, 宋青. 去甲肾上腺素与血管加压素改善脓毒症休克预后比较研究Meta分析[J]. 创伤与急危重病医学, 2013, 1(1): 49-53. ?

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