[高钰琪. 高原军事医学[M]. 重庆: 重庆出版社, 2005:? 206-212. [2]Yalcin O, Cabrales P. Increased hemoglobin O2 affinity protects during acute hypoxia[J]. Am J Physiol Heart Circ Physiol, 2012, 303(3):? H271-H281. [3]McCracken K G, Bulgarella M, Johnson K P, et al. Gene flow in the face of countervailing selection:? adaptation to high-altitude hypoxia in the betaA hemoglobin subunit of yellow-billed pintails in the Andes[J]. Mol Biol Evol, 2009, 26(4):? 815-827. [4]Natarajan C, Inoguchi N, Weber R E, et al. Epistasis among adaptive mutations in deer mouse hemoglobin[J]. Science, 2013, 340(6138):? 1324-1327. [5]McCracken K G, Barger C P, Sorenson M D. Phylogenetic and structural analysis of the HbA (alphaA/betaA) and HbD (alphaD/betaA) hemoglobin genes in two high-altitude waterfowl from the Himalayas and the Andes:? Bar-headed goose (Anser indicus) and Andean goose (Chloephaga melanoptera)[J]. Mol Phylogenet Evol, 2010, 56(2):? 649-658. [6]Mairbaurl H, Weber R E. Oxygen transport by hemoglobin[J]. Compr Physiol, 2012, 2(2):? 1463-1489. [7]Kregel K C, Allen D L, Booth F W, et al. Resource Book for the Design of Animal Exercise Protocols[M].Bethesda:? Am Physiol Soc, 2006:? 35-41. [8]杨涛, 黄庆愿, 单发波, 等. 急性高原低氧和力竭运动对大鼠骨骼肌AMPK磷酸化水平的影响[J]. 生理学报, 2012, 64(2):? 193-198. [9]Mendez I A, Montgomery K S, LaSarge C L, et al. Long-term effects of prior cocaine exposure on Morris water maze performance[J]. Neurobiol Learn Mem, 2008, 89(2): 185-191. [10]Debevec T, Pialoux V, Mekjavic I B, et al. Moderate exercise blunts oxidative stress induced by normobaric hypoxic confinement[J]. Med Sci Sports Exerc, 2014, 46(1):? 33-41. [11]王红阳, 韩晓庆, 赵雅宁, 等. 重度间歇低氧大鼠学习记忆功能与氧化应激的关系[J]. 中华结核和呼吸杂志, 2012, 35(1):? 24-28. [12]Al-Qahtani J M, Abdel-Wahab B A, Abd-El-Aziz S M. Long-term moderate dose exogenous erythropoietin treatment protects from intermittent hypoxia-induced spatial learning deficits and hippocampal oxidative stress in young rats[J]. Neurochem Res, 2014, 9(1):? 161-171. [13]Peng W, Wang X, Gao W, et al. In vitro kinetics of oxygen transport in erythrocyte suspension or unmodified hemoglobin solution from human and other animals[J]. Can J Physiol Pharmacol, 2011, 89(9):? 631-637. [14]Dugdale A. Shifts in the haemoglobin-oxygen dissociation curve:? can we manipulate P50 to good effect?[J]. Vet J, 2008. 175(1):? 12-13. [15]Hamilton C, Steinlechner B, Gruber E, et al. The oxygen dissociation curve:? quantifying the shift[J]. Perfusion, 2004, 19(3):? 141-144. [16]Zhang Y, Manning L R, Falcone J, et al. Human erythrocyte membrane band 3 protein influences hemoglobin cooperativity. Possible effect on oxygen transport[J]. J Biol Chem, 2003, 278(41):? 39565-39571. ?