Abulrob A, Brunette E, Slinn J, et al. Dynamic analysis of the blood-brain barrier disruption in experimental stroke using time domain in vivo fluorescence imaging[J]. Mol Imaging, 2008, 7(6): 248-262. [2]Barreto G, White R E, Ouyang Y, et al. Astrocytes: targets for neuroprotection in stroke [J]. Cent Nerv Syst Agents Med Chem, 2011, 11(2): 164-173. [3]Jiang P, Chen C, Wang R, et al. hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury [J]. Nat Commun, 2013, 4: 2196. [4]Lepore A C, Rauck B, Dejea C, et al. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease[J]. Nat Neurosci, 2008, 11(11): 1294-1301. [5]Shao W, Zhang S Z, Tang M, et al. Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin[J]. Nature, 2013, 494(7435): 90-94. [6]Bradbury E J, Kershaw T R, Marchbanks R M, et al. Astrocyte transplants alleviate lesion induced memory deficits independently of cholinergic recovery[J]. Neuroscience, 1995, 65(4): 955-972. [7]Han X, Chen M, Wang F, et al. Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice[J]. Cell Stem Cell, 2013, 12(3): 342-353. [8]郑向红, 许颖. 神经胶质细胞作用的研究进展[J]. 海峡药学, 2013, 25(3): 210-213. [9]Liu Y, Li C. Firing rate propagation through neuronal-astrocytic network[J]. IEEE Trans Neural Netw Learn Syst, 2013, 24(5): 789-799. [10]Santello M, Volterra A. Synaptic modulation by astrocytes via Ca2+-dependent glutamate release[J]. Neuroscience, 2009, 158(1): 253-259. [11]Orellana J A, Martinez A D, Retamal M A. Gap junction channels and hemichannels in the CNS: regulation by signaling molecules[J]. Neuropharmacology, 2013, 75: 567-582. [12]Tian G, Kong Q, Lai L, et al. Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease[J]. J Neurochem, 2010, 113(4): 978-989. [13]Tadimalla A, Belmont P J, Thuerauf D J, et al. Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart[J]. Circ Res, 2008, 103(11): 1249-1258. [14]Chu L F, Wang W T, Ghanta V K, et al. Ischemic brain cell-derived conditioned medium protects astrocytes against ischemia through GDNF/ERK/NF-κB signaling pathway[J]. Brain Res, 2008, 1239: 24-35. [15]Greenberg M L, Weinger J G, Matheu M P, et al. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis[J]. Proc Natl Acad Sci U S A, 2014, 111(22): E2349-E2355. [16]Barberi T, Klivenyi P, Calingasan N Y, et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice[J]. Nat Biotechnol, 2003, 21(10): 1200-1207. [17]Krencik R, Weick J P, Liu Y, et al. Specification of transplantable astroglial subtypes from human pluripotent stem cells[J]. Nat Biotechnol, 2011, 29(6): 528-534.