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大豆科学  2009 

基于混合并行遗传算法的大豆蛋白质二级结构预测

DOI: 10.11861/j.issn.1000-9841.2009.02.0200

Keywords: 大豆蛋白质,并行遗传算法,蛋白质二级结构预测,疏水序列

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Abstract:

大豆蛋白质是人类生活不可或缺的物质,对大豆蛋白质二级结构预测是能够准确预测蛋白质分子三维空间结构功能的关键步骤。将聚类分析、并行处理技术和遗传算法相结合,提出基于混合并行遗传算法(HPGA)的蛋白质二级结构预测方法,充分考虑蛋白质序列两端氨基酸对中间氨基酸结构的影响,蛋白质疏水性对二级结构的影响。在整合、改进前人算法的基础上使得计算复杂度降低1个数量级,使得预测准确率达到74%左右。

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