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催化学报  2011 

Fe3O4NanoparticlesasanEfficientandMagneticallyRecoverableCatalystfortheSynthesisof3,4-Dihydropyrimidin-2(1H)-onesunderSolvent-FreeConditions

DOI: 10.1016/S1872-2067(10)60263-X, PP. 1484-1489

Keywords: dihydropyrimidinones,dihydropyrimidinthiones,ferroferricoxidenanoparticle,one-potcondensation,solvent-free

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Abstract:

?ThecatalyticactivityofFe3O4nanoparticles(NPs)inaone-potthreecomponentcondensationreactionconsistingofanaromaticaldehyde,ureaorthiourea,andaβ-dicarbonylundersolvent-freeconditionswasinvestigated.Thisreactionaffordsthecorrespondingdihydropyrimidinones(thiones)inhightoexcellentyields.ComparedwiththeclassicalBiginellireactionsthismethodconsistentlygivesahighyield,easymagneticseparation,ashortreactiontime,andcatalystreusability.

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