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甘草次酸抗肿瘤作用机制的研究进展

Keywords: 甘草次酸,抗肿瘤,机制

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Abstract:

甘草次酸是中药甘草的主要有效成分之一。近年来,甘草次酸的抗肿瘤活性受到了广泛关注。研究表明,甘草次酸可以通过诱导肿瘤细胞凋亡、阻遏细胞周期、抑制肿瘤细胞侵袭、诱导肿瘤细胞分化、抑制肿瘤多药耐药等途径发挥抗癌作用,并能与化疗药物协同作用,对于促癌剂诱发的癌变也表现出一定的抑制功能。随着甘草次酸抗肿瘤作用机制的进一步阐明,其在肿瘤临床治疗中将具有广阔的开发应用前景。

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