Schuit S C, de Jong F H, Stolk L, et al. Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women[J]. Eur J Endocrinol, 2005, 153(2): 327.
Heard D J, Norby P L, Holloway J, et al. Human ERRg, a third member of the estrogen
[6]
Setchell K, Lydeking-Olsen E. Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies[J]. Am J Clin Nutr 2003,78(suppl):593S.
[7]
Huayue CHEN, Shoichi EMURA, Hideo ISONO, et al. Effects of traditional Chinese medicine on bone loss in SAMP6: a murine model for senile osteoporosis[J]. Biol Pharm Bull,2005,28 (5):865.
[8]
Bahram H, Arjmandi. The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency[J]. J Am Coll Nutr, 2001,20(suppl):398S.
[9]
Eriksen E F, Colvard D S, Berg N J, et al. Evidence of estrogen receptors in normal human osteoblast-like cells[J]. Science, 1988,241(4861):84.
[10]
Mano H, Yuasa T, Kameda T, et al. Mammalian mature osteoclast as estrogen target cells [J] .Bicochem Biophys Res Commun, 1996,223 (3):637.
D?ren M, Samsioe G. Prevention of postmenopausal osteoporosis with oestrogen replacement therapy and associated compounds: update on clinical trials since 1995[J]. Hum Reprod Update, 2000,6(5):419.
[19]
Pentti K, Honkanen R, Tuppurainen M T, et al. Hormone replacement therapy and mortality in 52- to 70-year-old women: the kuopio osteoporosis risk factor and prevention study[J]. Eur J Endocrinol, 2006,154(1):101.
[20]
Deady J. Clinical monograph: hormone replacement therapy [J]. J Manag Care Pharm, 2004,10(1):33.
[21]
Nikander E, Mets?-Heikkil? M, Ylikorkala O. Effects of phytoestrogens on bone turnover in postmenopausal women with a history of breast cancer [J]. J Clin Endocrnol Metab, 2004,89(3):1207.
Yamaguchi M, Sugimoto E. Stimulatory effect of genistein and daidzein on protein synthesis in osteoblastic MC3T3-El cells: activation of aminoacyl-tRNA synthetase[J]. Mol Cell Biochem,2000,214(1/2):97.
[36]
Marini H, Bitto A, Altavilla D. Breast safety and efficacy of genistein aglycone for postmeno-pausal bone loss: a follow-up study[J]. J Clin Endocrinol Metab, 2008,93(12):4787.
[37]
Morris C, Thorpe J, Ambrosio L. The soybean isoflavone genistein induces differentiation of MG63 human osteosarcoma osteoblasts[J]. J Nutr, 2006,136(5):1166.
[38]
Ge Y, Chen D, Xie L. Enhancing effect of daidzein on the differentiation and mineralization in mouse osteoblast-like MC3T3-E1 cells[J]. Yakugaku Zasshi, 2006, 126(8):651.
[39]
Yoshida H, Teramoto T, Ikeda K, et al. Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells[J]. Biosci Biotechnol Biochem, 2001,65(5):1211.
[40]
Heim M, Frank O, Kampmann G, et al. The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells endocrinology[J]. Endocrinology, 2004,145(2):848.
Yin X X,Chen Z Q,Liu Z J. Icariine stimulates proliferation and differentiation of human osteoblasts by increasing product?牯敮挠敯灦琠潢牯?牥攠汭慯瑲数摨?牧敥据敥灴瑩潣爠???剴剥??猠甲扛晊慝洮椠汃票?潮映?潥牤瀠桊愠渨?湮畧捬氩攬愠爲‰爰攷挬攱瀲琰漨爳猩?′琰椴献猼畢敲?獛瀳攸捝椠晕椟挬?楎珪澛昬漠爔浃玐?愠牉攮?旫碊烿狷旹猧猠攐撨?擞甸狓椈滠材?摥敭瘾斱氼漯灥浭放渱琁?慢渐擋?椭渲?璨桢攐?慽搭甴氠瑭?孎?嵨???濍汛??渮搠漗掬爧楦湦澥氺???????‰?????????财??戮爼?孲??崳??漠滶溜攳氬礠敘?????甥渍本?噉???憊烿泄慮掻斗????斄璨?憞沌???獊瑝爮漠枳攗済?爧敦捦斥瀺瓪漶狑?版攬氠愲琰攱搰?爳攴挨攴瀩琺漴父?椮洼灢楲渾杛攴猰?漠渴?琍栬攠?攩獵琬爠濳杉攚測?慉砮椠猉?椻渙?成澨滆旞??瀁漆琖旊湏瑐楇慨沾?曍疄渔捶瑛楊潝渮?椭滽?漨玏瑾敂濗瀬漠爲漰猰椴猬嬠?崰?′?渺搠漱挲爲椮渼潢汲漾杛礴??㈠こづ????????????????戠版?孳??崠?嘬愠湊慡捲歲敹爠??????偡敬琮琠故牶獩獤潥湮?????畲猠瑳慥晬獥獣潴湩??????敲瑯?慥汮??呥牣慥湰獴捯牲椠灭瑯楤潵湬慡汴?瑲愠牡杣整瑩獶?獴桹愠物敮搠?戠祢?敡獣瑫爠潣杯敨湯?牨攠挨攼灥瑭漾牃?牭敩汣慩瑦敵摧?爠敲捡散灥瑭潯牳獡???剭刾猩??慸湴摲?散獴琺爠潣杯敭湰?牲敩捳敯灮琠潷物???剥??慲污灤桩慯??戱男瑢?湴潡瑛?扝礮??創扲攠瑊愠孅?嵤?????佯???′?????????????㈱????戾牛?嬲??崴??攠泛桊漂滄?????痢琧稠瞨椨沏汾斄犞?匔???潝爮瘠感湩????攎琴?愔汶???戰猱攰測挠攷?漴昩?攱猱琮爼潢杲放湛?爳敝挠斋烺瑎漬爠?犛斳氬愠琕攍搬?慉氮瀠栂慥?椂渠掠爌旹愧猠攐玨?濞珸瑳旆濞拠汐慨玾瑱槍掄?撌椔晶晛敊牝攮渠琩椶憧瑩椔潶渎?懑測搠′挰愱渰挬攠氲氲漨申猩?戴漰渳攮?浢楲渾敛爴愴汝?摗敥湮獤楥琠祋嬬?嵋???湮搠潌挬爠楕湮潴汥潲杲祩???ひ??????????????????扶牥?嬠??嵴??楣杴畳牳整?噭??呡潴??剤剩?楦湥?瑥桮整?敡獴瑩牯潮朠敯湦?灨慵瑭桡睮愠祯孳?嵥??呬牡敳湴摩獣??湳摴潥捯牳楡湲潣汯??攠瑈慏打??㈠っづ???????????の??戠牍?孤??崲‰?愴氬氷攰琨????嘱愰渰愳挮欼敢牲 ̄??????勺劰?爠攠掇敳瀬琠濞牶珱?愠珇?灐澄琍敩滌瓀椠愷汜?瑛慊牝朮攠琭珽?榊溷?漬猠琲攰漰瀶漬爹漨猲椳猩嬺?崸??吼牢敲渾摛猴??渠搧漳捂犗椬渠潨沆??攠璓應戫????ㄠ[?????ヌ??????[J].中西医结合学报,2003,1(2):132.
[43]
García Palacios V, Robinson L J, Borysenko C W, et al. Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 Cells by estrogen and phytoestrogens [J]. J Biol Chem, 2005,280(14):13720.