Furusawa J, Funakoshi-Tago M, Mashino T, et al. Glycyrrhiza inflata-derived chalcones, licochalcone A, licochalcone B and licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway[J]. Int Immunopharmacol, 2009, 9 (4): 499.
[2]
Fukai T, Satoh K, Nomura T, et al. Antinephritis and radical scavenging activity of prenylflavonoids[J]. Fitoterapia, 2003, 74 (7/8) : 720.
[3]
崔永明. 甘草黄酮的分离鉴定、药效及其指纹图谱研究[D]. 武汉:华中科技大学, 2008.
[4]
Udompataikul M, Srisatwaja W. Comparative trial of moisturizer containing licochalcone A vs. hydrocortisone lotion in the treatment of childhood atopic dermatitis: a pilot study[J]. J Eur Acad Dermatol Venereol, 2011, 25 (6): 660.
[5]
Kolbe L, Immeyer J, Batzer J, et al. Anti-inflammatory efficacy of licochalcone A: correlation of clinical potency and in vitro effects[J]. Arch Dermatol Res, 2006, 298 (1): 23.
[6]
Qiu J, Feng H, Xiang H, et al. Influence of subinhibitory concentrations of licochalcone A on the secretion of enterotoxins A and B by Staphylococcus aureus[J]. FEMS Microbiol Lett, 2010, 307 (2): 135.
[7]
Qiu J, Jiang Y, Xia L, et al. Subinhibitory concentrations of licochalcone A decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates [J]. Lett Appl Microbiol, 2010, 50 (2): 223.
Messier C, Grenier D. Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans[J]. Mycoses, 2011, 54 (6): e801.
[10]
Tsukiyama R, Katsura H, Tokuriki N, et al. Antibacterial activity of licochalcone A against spore-forming bacteria[J]. Antimicrob Agents Chemother, 2002, 46 (5) : 1226.
[11]
Friis-Moller A, Chen M, Fuursted K, et al. In vitro antimycobacterial and antilegionella activity of licochalcone A from Chinese licorice roots [J]. Planta Med, 2002, 68 (5): 416.
[12]
Yadav N, Dixit S K, Bhattacharya A, et al. Antimalarial activity of newly synthesized chalcone derivatives in vitro[J]. Chem Biol Drug Des, 2012, 80 (2): 340.
[13]
Mi-Ichi F, Miyadera H, Kobayashi T, et al. Parasite mitochondria as a target of chemotherapy: inhibitory effect of licochalcone A on the Plasmodium falciparum respiratory chain[J]. Ann N Y Acad Sci, 2005, 1056: 46.
[14]
Mishra L C, Bhattacharya A, Bhasin V K. Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro [J]. Acta Trop, 2009, 109 (3): 194.
[15]
Ziegler H L, Hansen H S, Staerk D, et al. The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed[J]. Antimicrob Agents Chemother, 2004, 48 (10): 4067.
[16]
Zhai L, Blom J, Chen M, et al. The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria [J]. Antimicrob Agents Chemother, 1995, 39 (12): 2742.
[17]
Chen M, Zhai L, Christensen S B, et al. Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones [J]. Antimicrob Agents Chemother, 2001, 45 (7): 2023.
[18]
Kim S N, Kim M H, Min Y K, et al. Licochalcone A inhibits the formation and bone resorptive activity of osteoclasts[J]. Cell Biol Int, 2008, 32 (9): 1064.
[19]
Lee C S, Kwak S W, Kim Y J, et al. Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways[J]. Eur J Pharmacol, 2012, 683 (1/3):54.
[20]
Rafi M M, Rosen R T, Vassil A, et al. Modulation of bcl-2 and cytotoxicity by licochalcone-A, a novel estrogenic flavonoid[J]. Anticancer Res, 2000, 20 (4) : 2653.
[21]
Xiao X Y, Hao M, Yang X Y, et al. Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosis[J]. Cancer Lett, 2011, 302 (1) : 69.
[22]
Kim Y H, Shin E K, Kim D H, et al. Antiangiogenic effect of licochalcone A[J]. Biochem Pharmacol, 2010, 80 (8) : 1152.
[23]
Fu Y, Hsieh T C, Guo J, et al. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells [J]. Biochem Biophys Res Commun, 2004, 322 (1): 263.
[24]
Kim J K, Shin E K, Park J H, et al. Antitumor and antimetastatic effects of licochalcone A in mouse models [J]. J Mol Med (Berl), 2010, 88 (8) : 829.
[25]
Park E J, Park H R, Lee J S, et al. Licochalcone A: an inducer of cell differentiation and cytotoxic agent from Pogostemon cablin [J]. Planta Med, 1998, 64 (5) : 464.
[26]
Szliszka E, Czuba Z P, Mazur B, et al. Chalcones enhance TRAIL-induced apoptosis in prostate cancer cells [J]. Int J Mol Sci, 2009, 11(1): 1.
[27]
Lee C K, Son S H, Park K K, et al. Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice [J]. Basic Clin Pharmacol Toxicol, 2008, 103 (1): 48.
[28]
Yoon G, Kang B Y, Cheon S H. Topoisomerase I inhibition and cytotoxicity of licochalcones A and E from Glycyrrhiza inflate [J]. Arch Pharm Res, 2007, 30 (3) : 313.
[29]
Yo Y T, Shieh G S, Hsu K F, et al. Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway [J]. J Agric Food Chem, 2009, 57 (18) : 8266.
Funakoshi-Tago M, Tago K, Nishizawa C, et al. Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation [J]. Biochem Pharmacol, 2008, 76 (12) : 1681.
[32]
Kwon H S, Park J H, Kim D H, et al. Licochalcone A isolated from licorice suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice [J]. J Mol Med(Berl), 2008, 86 (11) : 1287.
[33]
Funakoshi-Tago M, Tanabe S, Tago K, et al. Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation[J]. Mol Pharmacol, 2009, 76 (4): 745.
[34]
Kim S N, Bae S J, Kwak H B, et al. In vitro and in vivo osteogenic activity of licochalcone A[J]. Amino Acids, 2012, 42 (4): 1455.
[35]
Barfod L, Kemp K, Hansen M, et al. Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines[J]. Int Immunopharmacol, 2002, 2 (4): 545.
[36]
Nagai H, He J X, Tani T, et al. Antispasmodic activity of licochalcone A, aspecies-specific ingredient of Glycyrrhiza inflata roots[J]. J Pharm Pharmacol, 2007, 59 (10): 1421.
[37]
Park J H, Lim H J, Lee K S, et al. Anti-proliferative effect of licochalcone A on vascular smooth muscle cells[J]. Biol Pharm Bull, 2008, 31 (11): 1996.
[38]
Quan H Y, Baek N I, Chung S H. Licochalcone A prevents adipocyte differentiation and lipogenesis via suppression of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein pathways[J]. J Agric Food Chem, 2012, 60 (20): 5112.
