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白木香叶的化学成分研究(二)

Keywords: 沉香属,白木香叶,二苯甲酮,黄酮苷,酚类

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Abstract:

为综合利用白木香叶的丰富资源,阐明其物质基础,课题组再次对其化学成分进行了研究,采用多种色谱技术对其化学成分进行分离纯化,从白木香叶95%,70%乙醇提取物的氯仿和正丁醇萃取部位共分离得到12个化合物.经多种波谱方法鉴定其结构,分别为鸢尾酚酮2-(O-α-L)-吡喃鼠李糖苷(3),4'-羟基-5-甲氧基黄酮-7-O-葡萄糖(6-1)木糖苷(2),7,3',5'-三甲氧基黄酮苷(3),5-甲氧基芹菜素7-(O-β-D)-葡萄糖苷(4),2-苯乙基1-O-β-D-吡喃葡萄糖苷(5),红景天苷(6),苯甲醇1-O-β-D-吡喃葡萄糖苷(7),2,6-二甲氧基-4-羟基苯酚-1-O-β-D-吡喃葡萄糖苷(8),vanilloloside(9),(+)-丁香脂素(10),β-维生素E(11),豆甾-5-烯-3β,7α-二醇(12),化合物2,3,5~9,11和12为首次从该属植物中分离得到.另外,对氯仿萃取部位的9个流分进行了4种人体肿瘤细胞毒活性筛选,均未显示明显活性.

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