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加拿大红豆杉中紫杉烷类成分的研究进展及药源危机解决方法探讨

Keywords: 加拿大红豆杉,化学成分,紫杉烷类化合物,紫杉醇,抗肿瘤

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Abstract:

加拿大红豆杉产于北美洲,主要分布在北明尼苏达州、纽芬兰、南威斯康辛州、宾夕法尼亚州。很多研究已证明加拿大红豆杉中的化学成分与其他种有很多差异,并且近年来还在加拿大红豆杉中发现了一些新骨架。通过对多种红豆杉植物所含有紫杉烷类化合物含量的分析,结果表明加拿大红豆杉中紫杉醇含量较高。该文结合文献近年来对加拿大红豆杉的研究工作,重点对近年来加拿大红豆杉中紫杉烷类化学成分研究进展及各型化合物的波谱特征进行综述,并探讨解决紫衫醇药源危机方法的研究现状。

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