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独蒜兰的化学成分研究

Keywords: 山慈菇,独蒜兰,菲及二氢菲类,联苄类

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Abstract:

应用硅胶、ODS、大孔树脂、葡聚糖凝胶SephadexLH-20和HPLC等多种色谱分离方法相结合,从中药山慈菇来源之一——独蒜兰干燥假鳞茎的95%乙醇提取物的醋酸乙酯萃取部位中分离得到14个化合物,其中菲及二氢菲类10个,联苄类2个,木脂素1个,甾醇1个;根据化合物的波谱数据鉴定化合物的结构为monbarbatainA(1),2,7,2'-三羟基-4,4',7'-三甲氧基-1,1'-二聚菲(2),白芨烯A(3),pleionesinB(4),shanciolH(5),{7-hydroxy-7'-(4'-hydroxy-3'-methoxyphenyl)-4-methoxy-9,10,7',8'-tetrahydrophenanthro[2,3-b]furan-8'-yl}methylacetate(6),2,7-二羟基-1-(对羟基苄基)-4-甲氧基菲(7),2,7-二羟基-1-(对-羟基苄基)-4-甲氧基-9,10-二氢菲(8),赫尔西酚(9),贝母兰宁(10),石斛酚(11),山药素Ⅲ(12),丁香脂素(13),麦角甾-4,6,8(14),22-四烯-3-酮(14)。其中化合物1-3,9,13,14为首次从该属植物中分离得到。

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