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MicroRNA与高血压病

Keywords: miRNA,高血压,发病机制,治疗

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Abstract:

MicroRNA在高血压病的发生发展中起到重要的作用,包括对肾素血管紧张素醛固酮系统的过激反应,血管内皮的功能紊乱,血管平滑肌的影响,而维持和恢复靶器官中相应miRNA的稳定表达可能成为高血压病治疗的一个新靶点。miRNA的调控过程的阐明和特定miRNA在高血压的靶点的明确将是一项非常有价值,非常激动人心的研究。可能将高血压的治疗方法引领向新的高度。回顾miRNA与高血压病的发病机制,以及miRNA作为生物标志物以及治疗靶点的研究,为今后的研究提供重要借鉴是非常必要的。

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