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独蒜兰中丁二酸苄酯苷类化学成分的研究

Keywords: 山慈菇,独蒜兰,丁二酸苄酯苷类化合物,抗痴呆活性

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Abstract:

应用反相硅胶ODS、大孔树脂、葡聚糖凝胶SephadexLH-20和HPLC等多种色谱分离技术,从中药山慈菇来源之一——独蒜兰Pleionebulbocodioides干燥假鳞茎中分离得到10个丁二酸苄酯苷类化合物和1个苄醇糖苷类化合物,根据理化性质和波谱数据分别鉴定为loroglossin(1),grammatophyllosideA(2),cronupapine(3),(-)-(2R,3S)-1-[4-(β-D-吡喃葡萄糖氧)苄基]-4-甲基-2-异丁基酒石酸酯(4),vandaterosideⅡ(5),grammatophyllosideB(6),(-)-(S)-1,4-二-[4-(β-D-吡喃葡萄糖氧)苄基]-2-异丙基苹果酸酯(7),gymnosideⅠ(8),militarine(9),dactylorhinA(10),天麻苷(11)。其中化合物1~7为首次从独蒜兰属植物中分离得到。

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