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黄芩素对帕金森病的神经保护作用

Keywords: 黄芩素,帕金森病,神经保护作用

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Abstract:

黄芩素是从传统中药黄芩的干燥根中提取的黄酮类化合物,具有抗炎和抗氧化作用。随着其作用机制的不断研究,近些年发现黄芩素在帕金森病等神经系统退行性疾病的临床症状改善和神经保护方面也有一定的效果。目前研究发现其神经保护机制与抗炎,抑制氧化应激,保护线粒体,拮抗谷氨酸神经毒性,神经生长因子样作用以及抑制α-synuclein聚集等密切相关。该文从黄芩素对帕金森病的神经保护方面进行综述。

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