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血管内皮细胞-平滑肌细胞共培养体系研究进展

Keywords: 内皮细胞,平滑肌细胞,共培养,相互作用

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Abstract:

血管内皮细胞(endothelialcells,EC)和血管平滑肌细胞(smoothmusclecells,VSMC)的相互作用、相互影响维持血管生理功能和多种疾病的发生发展,EC-SMC联合培养模型是目前研究这2种细胞间相互影响的最佳方式。作者对现有的EC-SMC共培养模型及共培养对这2种细胞结构和功能的影响进行综述,为在微观上深入研究二者的相互关系提供依据,也为建立更接近机体生理/病理状态的EC-SMC体外共培养体系提供参考。

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