Peng C H, Huang C N, Hsu S P, et al. Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells[J]. Toxicology, 2007(238):130.
Yukio K. Formation of nitrogen-containery metabolites from geniposide and gardenoside by human intestinal bacteria[J]. Planta-Med,1991,57(6):536.
[18]
Yim J S, Kim Y S, Moon S K, et al. Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora[J]. Biol Pharm Bull,2004,27(10):1580.
Teruaki A. Enzymic studies on the animal and intestinal metabolism of geniposide[J]. Bio Pharm Bull,1994,17(2):1573.
[22]
Wu S Y, Wang G F, Liu Z Q, et al. Effect of geniposide, ahypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin[J]. Acta Pharmacol Sin,2009,30(12):202.
Mikami M, Takikawa H. Effect of genipin on the biliary excretion of cholephilic compounds in rats[J]. Hepatol Res,2008,38(6):614.
[25]
Junichi S,Tetsuo M,Hirotoshi U,et al. Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver[J]. Hepatology,2004, 39(1):167.
[26]
Kuo W H, Wang C J, Young S C, et al. Differential induction of the expression of GST subunits by geniposide in rat hepatocytes[J]. Pharmacology,2004,70:15.
[27]
Kim B C, Kim H G, Lee S A, et al. Genipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway[J]. Biochem Pharm,2005,70(9):1398.
[28]
Liu J H, Yin F, Guo L X, et al. Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury : involvement of PI3 kinase signal pathway[J]. Acta Pharmacol Sin,2009,30(2):159.
[29]
Liu J H, Yin F, Zheng X X, et al. Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway[J]. Neurochem Int,2007,51(6/7):361.
[30]
Peng C H, Huang C N, Wang C J, et al. The anti-tumor effect and mechanisms of action of penta-acetyl geniposide[J]. Current Cancer Drug Targets,2005,5:299.
[31]
Huang H P, Shih Y W, Wu C H, et al. Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways[J]. Chem Biol Interact, 2009,181(1):8.