Verpoorte R, Crommelin D, Danhof M, et al. Commentary: "a systems view on the future of medicine: inspiration from Chinese medicine?"[J]. J Ethnopharmacol, 2009, 121 (3): 479.
[2]
Li P, Yang L P, Gong Y W. Application of systems biology technology in research of traditional Chinese medicine[J]. J Trad Chin Med, 2009, 29 (2): 153.
[3]
Schmidt B M, Ribnicky D M, Lipsky P E, et al. Revisiting the ancient concept of botanical therapeutics[J]. Nat Chem Biol, 2007, 3 (7): 360.
[4]
Barabasi A L, Oltvai Z N. Network biology: understanding the cell\'s functional organization[J]. Nat Rev Genet, 2004, 5 (2): 101.
[5]
Sengupta U, Ukil S, Dimitrova N, et al. Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications[J]. PloS One, 2009, 4 (12):e8100.
[6]
Lee D, Hwang S, Son S W, et al. A protein interaction network associated with asthma[J]. J Theor Biol, 2008, 252 (4):722.
[7]
Chen B S, Chu L H. Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets[J]. Bmc Syst Biol, 2008,2:56.
[8]
Nielsen U B, Schoeberl B, Pace E A, et al. Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis[J]. Sci Signal, 2009, 2 (77):ra33.
[9]
Li S, Zhao S W. Network-based relating pharmacological and genomic spaces for drug target identification[J]. PloS One, 2010, 5 (7):e11597.
[10]
Hopkins A L. Network pharmacology: the next paradigm in drug discovery[J]. Nat Chem Biol, 2008, 4 (11): 682.
[11]
Xu X J, Zhu W, Qiu X H, et al. Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease[J]. Sci China Chem, 2010, 53 (11): 2337.
Watts D J, Strogatz S H. Collective dynamics of \'small-world\' networks[J]. Nature, 1998, 393 (6684): 440.
[17]
Barabasi A L, Albert R. Emergence of scaling in random networks[J]. Science, 1999, 286 (5439):509.
[18]
Newman M E J. The structure and function of complex networks[J]. Siam Rev, 2003, 45(2): 167.
[19]
Ideker T, Galitski T, Hood L. A new approach to decoding life: systems biology[J]. Annu Rev Genomics Hum Genet, 2001, 2:343.
[20]
Wang L, Zhou G B, Liu P, et al. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia[J]. Proc Natl Acad Sci USA, 2008, 105 (12):4826.
[21]
Chen M J, Su M M, Zhao L P, et al. Metabonomic study of aristolochic acid-induced nephrotoxicity in rats[J]. J Proteome Res, 2006, 5 (4): 995.
[22]
Chen M J, Zhao L P, Jia W. Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model[J]. J Proteome Res,2005, 4 (6): 2391.
[23]
Wang X Y, Su M M, Qiu Y P, et al. Metabolic regulatory network alterations in response to acute cold stress and ginsenoside intervention[J]. J Proteome Res, 2007, 6 (9):3449.
[24]
Auffray C, Chen Z, Hood L. Systems medicine: the future of medical genomics and healthcare[J]. Genome Med, 2009, 1(1):1.
Barabási A L, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease[J]. Nat Rev Genet, 2011, 12 (1):56.
[27]
Stelzl U, Worm U, Lalowski M, et al. A human protein-protein interaction network: A resource for annotating the proteome[J]. Cell, 2005, 122 (6):957.
[28]
Lee S, Park K, Kim D. Building a drug-target network and its applications[J]. Expert Opinion on Drug Discovery, 2009, 4 (11):1177.
[29]
Yildirim M A, Goh K I, Cusick M E, et al. Drug-target network[J]. Nat Biotechnol, 2007, 25 (10): 1119.
[30]
Goh K I, Cusick M E, Valle D, et al. The human disease network[J]. Proc Natl Acad Sci USA, 2007, 104 (21): 8685.
[31]
Lee D S, Park J, Kay K A, et al. The implications of human metabolic network topology for disease comorbidity[J]. Proc Natl Acad Sci USA,2008, 105 (29): 9880.
[32]
Jeong H, Tombor B, Albert R, et al. The large-scale organization of metabolic networks[J]. Nature, 2000, 407 (6804):651.
[33]
Ma H W, Goryanin I. Human metabolic network reconstruction and its impact on drug discovery and development[J]. Drug Disc Today, 2008, 13 (9/10):402.
