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比较效益研究的设计、实施和分析方法概述

Keywords: 比较效益研究,中医临床研究,研究设计

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Abstract:

比较效益研究(comparativeeffectivenessresearch,CER)被认为是一种可以提升医疗卫生研究质量的有力工具,该工具从策略层面上有益降低医疗卫生成本。比较效益研究的提出仍然源自于"效力"和"效果"的研究问题。以往的效力研究总是在较为严格的控制条件下探索干预措施是否有效,而现今的医学研究除了探索有效之外,更关注针对谁有效,在哪一种情况下有效的效果问题。过去经典的效力研究常通过比较一种新干预措施和安慰剂,来获得其效力的评价。现今CER发展到对两种或多种不同干预措施进行直接对比,而且强调在尽可能接近临床实际减少人为控制因素的情况下进行对比。该文通过对系列文献和报告的归纳和总结,就如何设计、实施、分析CER,进行了分析和综述,为以后中医药研究者开展类似研究提供参考。

References

[1]  Garrison LP Jr, Neumann P J, Radensky P,et al. A flexible approach to evidentiary standards for comparative effectiveness research [J]. Health Aff (Millwood), 2010,29(10):1812.
[2]  Sox H C. Comparative effectiveness research: a progress report[J]. Ann Intern Med, 2010,153(7):469.
[3]  Dreyer N A, Tunis S R, Berger M, et al. Why observational studies should be among the tools used in comparative effectiveness research[J]. Health Aff (Millwood), 2010,29(10):1818.
[4]  Patient Protection Affordable Care Act-H. R. 3590. 2012-8-10.http://www.opencongress.org/bill/111-h3590/show.
[5]  Institute of Medicine. Initial national priorities for comparative effectiveness research[M]. Washington, DC: The National Academies Press, 2009.
[6]  Federal Coordinating Council for Comparative Effectiveness Research. Report to the president and congress. Washington, DC: Department of Health and Human Services, 2009.
[7]  Lind J. A treatise of the scurvy in three parts[M]. London: A Millar, 1753.
[8]  Mamdani M, McNeely D, Evans G, et al. Impact of a uoroquinolone restriction policy in an elderly population [J]. Am J Med,2007,120:893.
[9]  Eden J, B Wheatley, B J McNeil, et al. Knowing what works in health care: a roadmap for the nation[M]. Washington, DC: National Academies Press,2008.
[10]  VanLare J M, Conway P H, Sox H C N. Five next steps for a new national program for comparative-effectiveness research [J]. Engl J Med,2010, 362(11):970.
[11]  Good ReseArch for Comparative Effectiveness.2013-1-7. http://www.graceprinciples.org/.
[12]  Berger M L, Mamdani M, Atkins D, et al.Good research practices for comparative effectiveness research: defining, reporting and interpreting nonrandomized studies of treatment effects using secondary data sources: the ISPOR good research practices for retrospective database analysis task force report-Part I [J].Value Health,2009,12(8):1044.
[13]  Cox E, Martin B C, Van Staa T,et al. Good research practices for comparative effectiveness research: approaches to mitigate bias and confounding in the design of nonrandomized studies of treatment effects using secondary data sources: the international society for pharmacoeconomics and outcomes research good research practices for retrospective database analysis task force repor-Part II[J].Value Healt
[14]  Conway P H, Clancy C. Charting a path from comparative effectiveness funding to improved patient-centered health care[J]. J Amer Med Assoc, 2010,303(10):985.
[15]  谢雁鸣,廖星,王永炎.将比较效益研究理念引入中医临床评价研究[J].中西医结合学报,2011,9( 8): 813.
[16]  谢雁鸣,廖星.对比较效益研究GRACE准则的解析[J].中国中西医结合杂志,2012,32(8):1121.
[17]  Institute of Medicine. Learning what works best: The nation\'s need for evidence on comparative effectiveness in health care 2007. 2013-1-7. http://www.iom.edu/ebm-effectiveness.
[18]  Congressional Budget Office. Research on the comparative effectiveness of medical treatments. 2012-7-8. http://www.cbo.gov/publication/41655.
[19]  C Schoen, S Guterman, A Shih J,et al. Bending the curve: options for achieving savings and improving value in U.S. health spending.. 2012-7-8. http://www.commonwealthfund.org/publ...doc_id=620087 on 12/18/2007.
[20]  Concato J, Peduzzi P, Huang GD, et al. Comparative effectiveness research: what kind of studies do we need? [J]. J Investig Med, 2010, 58(6):764.
[21]  Michael Hochman, Danny McCormick. Characteristics of published comparative effectiveness studies of medications[J]. J Amer Med Assoc, 2010,303(10):951.
[22]  Hove E, Pittman P. A first look at the volume and cost of comparative effectiveness research in the united atates[M]. Washington, DC: Academy Health, 2009.
[23]  Erin Holve, Patricia Pittman.Cost and volume of current comparative effectiveness research..http://www.nhpf.org/library/handouts/Holve.slides_10-03-08.pdf.
[24]  William Wang, Nancy Santanello. Study designs in comparative effectiveness research.. http://coresummit.org/doc/William_Wang.pdf.
[25]  Federal Coordinating Council for Comparative Effectiveness Research. Report to the president and the congress.. http://www.hhs.gov/recovery/programs/cer/cerannualrpt.pdf.
[26]  Rockville M D. Methods guide for effectiveness and comparative effectiveness reviews.. http://www.effectivehealthcare.ahrq.gov/ehc/products/60/318/Meth桯??ぇふ?????????ぢ????扴物?孮??嵲??潴桟渲猰漱渲‰?′????牦漮眼湢?圾?′?慝爠瑍楥湤??????敡瑲?愮氮?‰?漲漭搸?爷攮獨整慴牰挺栯?灪牯慵捲瑮楡捬敳献?晷潷爮?捯潭洯灬慷牷愭瑭楥癤敩?敡晬晣敡捲瑥椯癴敯湣支猲猰?爰支猰收愰爰挱栮??慲渾慛氲礲瑝椠捍?浤敩瑣桡潬搠獃?瑲潥?椮洲瀰爱漲瘭攸?挷愮畨獴慴汰?椯港晪敯牵敲湮捡敬?昮牬潷海?湣潯湭爯慬湷摷漭浭楥穤敩摣?獬瑣畡摲楥支獴?潣是′琰爰攷愯琱洰攰渰琲?攼晢晲放捛琲猳?甠獓楥湡杮?獔敵据潩湳搠慍爠祄?搠慃瑯慭?獡潲畡牴捩敶獥??瑦桦敥??卩偶佥剮?杳潳漠摲?牳敥獡敲慣牨挠桭?灴牨慯捤瑳椠捡敮獤?晲潥牳?牡敲瑣牨漠獩灮敦捲瑡楳癴敲?摣慴瑵慲扥愮献攠′愰渱愲氭礷猭椸献?瑨慴獴歰?是漯牷捷敷?牥敨灣潣牡琮?偯慭爯瑰????孮?嵡?噩慯汮畳支??敭慰汥瑦桦???どぶ??????????????戮爼?孲??崲??匠偖佯剮?杅潬潭搠?瀬爠慁捬瑴業捡敮猠?映潇爬?潐畯瑣捯潣浫攠獓?牊攬猠敥慴爠捡桬?椠湓摴敲硥???と????????桥琠瑲灥???睴睩睮?椠獯灦漠牯?潳牥杲?睡潴物歯灮慡灬攠牳?灵牤慩捥瑳椠捩敮猠彥楰湩摤敥硭?慯獬灯?y (STROBE) statement: guidelines for reporting observational studies [J]. Bri Med J, 2007,335:806.
[27]  Greenland S. Confounding and exposure trends in case-crossover and case-time-control designs[J]. Epidemiology, 1996, 7:231.

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