3 Lippuner K. The future of osteoporosis treatment—A research update. Swiss Med Wkly, 2012, 142: 1-11
[2]
14 Nie J, Liu L, He F C, et al. CKIP-1: A scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions. Ageing Res Rev, 2013, 12: 276-281
[3]
15 Cui Y, He S, Xing C C, et al. SCFFBXL regulates BMP signaling by directing the degradation of HECT-type ubiquitin ligase Smurf1. EMBO J, 2011, 30: 2675-2689
[4]
17 Ng K W. Potential role of odanacatib in the treatment of osteoporosis. Clin Interv Aging, 2012, 7: 235-247
[5]
18 Toulis K A, Anastasilakis A D, Polyzos S A, et al. Targeting the osteoblast: Approved and experimental anabolic agents for the treatment of osteoporosis. Hormones, 2011, 10: 174-195
[6]
19 Baron R, Hesse E. Update on bone anabolics in osteoporosis treatment: Rationale, current status, and perspectives. J Clin Endocrinol Metab, 2012, 97: 311-325
[7]
20 Zhang G, Guo B S, Wu H, et al. A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nat Med, 2012, 18: 307-314
[8]
1 Ernesto C. New treatment modalities in osteoporosis. Endocr Pract, 2010, 16: 855-863
4 Tsourdi E, Rachner T D, Rauner M, et al. Denosumab for bone diseases: Translating bone biology intotargeted therapy. Eur J Endocrinol, 2011, 165: 833-840
[11]
5 Kim J H, Liu X, Wang J H, et al. Wnt signaling in bone formation and its therapeutic potential for bone diseases. Ther Adv Musculoskelet Dis, 2013, 5: 13-31
[12]
6 Rachner T D, Khosla S, Hofbauer L C, et al. New horizons in osteoporosis. Lancet, 2011, 377: 1276-1287
[13]
7 Ke H Z, Richards W G, Li X D, et al. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr Rev, 2012, 33: 747-783
11 Cao Y, Zhang L Q. A Smurf1 tale: Function and regulation of an ubiquitin ligase in multiple cellular networks. Cell Mol Life Sci, 2013, 70: 2305-2317
[18]
12 Cao Y, Zhang L Q. Pharmaceutical perspectives of HECT-TYPE ubiquitin ligase smurf1. Curr Pharm Design, 2013, 19: 3226-3233
[19]
13 Lu K F, Yin X S, Weng T J, et al. Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1. Nat Cell Biol, 2008, 10: 994-1002
[20]
16 Das S, Crockett J C. Osteoporosis—A current view of pharmacological prevention and treatment. Drug Des Devel Ther, 2013, 7: 435-448
