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科学通报  2015 

钯催化下N-亚硝基导向的芳环上氨基邻位C(sp2)-H键的直接酰氧基化反应

DOI: 10.1360/N972015-00159, PP. 2942-2948

Keywords: ,芳胺,酰氧基化,碳氢键活化,催化

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Abstract:

以醋酸钯为催化剂,通过对芳环sp2碳氢键的活化,实现了一个高区域选择性的芳环上氨基邻位的直接酰氧基化反应.该反应具有良好的官能团兼容性,当苯环上有给电子基或一般吸电子基时反应均可发生.该方法具有反应条件温和、操作简单、条件易于控制、产率较高等优点.对可能的反应机理提出了建议.

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