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科学通报  2011 

有机合成中钯催化交叉偶联反应:2010年诺贝尔化学奖成果简介

DOI: 10.1360/972010-2159, PP. 995-1006

Keywords: Heck,反应,Negishi,反应,Suzuki-Miyaura,反应,,交叉偶联反应

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Abstract:

瑞典皇家科学院将2010年诺贝尔化学奖授予美国和日本的3位科学家理查德·海克(RichardF.Heck)、根岸英一(Ei-ichiNegishi)和铃木章(AkiraSuzuki),以表彰他们在“有机合成中钯催化交叉偶联反应”方面所做出的杰出贡献.他们的研究成果极大地促进了有机合成化学的发展,广泛应用于合成制备具有特殊光电功能的高性能有机电子材料、具有复杂结构的天然产物和生物活性化合物以及一些精细化学品,对学术界和工业界产生了重要影响.本文简要介绍了Heck反应、Negishi反应和Suzuki-Miyaura反应的基本知识,并讨论了其发展和应用概况.

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