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科学通报  2013 

太原市学龄前儿童哮喘、过敏性鼻炎及湿疹与出生前及早期家居环境的相关性

, PP. 2570-2576

Keywords: 潮湿,室内,家具,霉菌,有机挥发物

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Abstract:

为了探讨出生前及早期家居生活环境与儿童的哮喘及过敏性疾病的相关性,在山西省太原市区学龄前儿童(3700名)中开展了一项横断面流行病学研究.研究采用问卷调查的方式,问卷内容包括儿童的哮喘和相关过敏性疾病的患病情况,采用了InternationalStudyonAsthmaandAllergiesinChildhood(ISAAC)的核心问卷;儿童的家居生活环境采用了瑞典的DampnessinBuildingsandHealth(DBH)的问卷内容,并根据中国的生活习惯进行了部分调整.通过多因素Logistic回归分析并调整了儿童年龄、性别、家族遗传,市区或郊区/农村,被动吸烟和母乳喂养,结果显示,出生前(指母亲怀孕前一年或/和怀孕期间)居住地添置新家居(HNF)与儿童报告的既往哮鸣音[比对比(OR)1.23,95%置信区间CI(1.03~1.48)],及过去12个月内的哮鸣音(1.24,1.00~1.54)、鼻炎症状(1.26,1.06~1.51)以及湿疹(1.42,1.01~1.99)呈正相关.在0~1岁间的HNF与过去12个月的哮鸣音症状,及0~1岁间家里新装修(HND)与儿童的既往鼻炎及过去12个月鼻炎和湿疹的症状均呈现正相关.室内发霉的迹象或室内潮湿几乎与所有儿童的哮喘和过敏性疾病的症状呈现更强的正相关(OR范围在1.23~1.85,P

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