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菌物学报  2015 

海洋真菌菌核青霉FS50固体发酵代谢产物

DOI: 10.13346/j.mycosystema.130169, PP. 117-123

Keywords: 海洋真菌,菌核青霉,异香豆素,结构鉴定

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Abstract:

采用硅胶柱、反相硅胶柱、凝胶柱、薄层制备和HPLC等色谱技术对1株分离自南海沉积物的海洋真菌菌核青霉PenicilliumsclerotiorumFS50的大米发酵提取物进行分离纯化,从中分离得到7个化合物。通过波谱数据分析,化合物1?7分别被鉴定为:6,8-dihydroxyisocoumarin-3-butylformate(1),6,8-dihydroxyisocoumarin-3-carboxylicacid(2),6-methoxy-8-hydroxyisocoumarin-3-carboxylicacid(3),(+)-sclerotiorin(4),4-methyl-5,6-dihydropyren-2-one(5),5-羟甲基糠醛(6),胡萝卜甙(7)。化合物1为新化合物,化合物2,3,6为首次从青霉属中分离得到。

References

[1]  Arunpanichlert J, Rukachaisirikul V, Sukpondma Y, Phongpaichit S, Tewtrakul S, Rungjindamai N, Sakayaroj J, 2010. Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13. Chemical and Pharmaceutical Bulletin, 58(8): 1033-1036 [本文引用:1]
[2]  Ayer WA, Racok JS, 1990. The metabolites of Talaromyces flavus: Part 1. Metabolites of the organic extracts. Canadian Journal of Chemistry, 68(11): 2085-2094 [本文引用:1]
[3]  Baek NI, Han JT, Ahn EM, Park JK, Cho SW, Jeon SG, Jang JS, Kim CK, Choi SY, 2000. Isolation of anticonvulsant compounds from the fruits of Schizand ra chinensis Baill. Agricultural Chemistry & Biotechnology, 43: 72-77 [本文引用:1]
[4]  Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR, 2012. Marine natural products. Natural Product Reports, 29: 144-222 [本文引用:1]
[5]  Blunt JW, Copp BR, Munro MHG, Northcote PT, Prinsep MR, 2011. Marine natural products. Natural Product Reports, 28: 196-268 [本文引用:1]
[6]  Chavez R, Bull P, Eyzaguirre J, 2006. The xylanolytic enzyme system from the genus Penicillium. Journal of Biotechnology, 123(4): 413-433 [本文引用:1]
[7]  Cho EJ, Choi JY, Lee KH, Lee S, 2012. Isolation of antibacterial compounds from Parasenecio pseudotaimingasa. Horticulture, Environment, and Biotechnology, 53(6): 561-564 [本文引用:1]
[8]  Dai YC, Yang ZL, 2008. A revised checklist of medicinal fungi in China. Mycosystema, 27: 801-824 (in Chinese) [本文引用:1]
[9]  Gokmen V, Acar J, 1999. Simultaneous determination of 5-hydroxymethylfurfural and patulin in apple juice by reversed-phase liquid chromatography. Journal of Chromatography A, 847(1): 69-74 [本文引用:1]
[10]  Le DH, Takenaka Y, Hamada N, Miyawaki H, Tanahashi T, 2013. A 14-membered macrolide and isocoumarin derivatives from the cultured lichen mycobionts of Graphis vestitoides. Chemical & Pharmaceutical Bulletin, 61(3): 358-362 [本文引用:1]
[11]  Li L, Yang JF, Yuan XA, 2005. Study on synthesis of isocoumarins and its evolution. Journal of Nanjing Normal University (Engineering and Technology), 5(2): 64-67 (in Chinese) [本文引用:1]
[12]  Li QX, Shi XF, Huang Z, Tian XP, Wang FZ, 2013. Indole alkaloids from marine-derived fungi: structures and activities. Journal of Tropical Oceanography, 32(1): 35-47 (in Chinese) [本文引用:1]
[13]  Lucas EMF, Castro MC, Takahashi JA, 2007. Antimicrobial properties of sclerotiorin, isochromophilone VI and pencolide, metabolites from a Brazilian cerrado isolate of Penicillium sclerotiorum van Beyma. Brazilian Journal of Microbiology, 38(4): 785-789 [本文引用:1]
[14]  Matsumoto N, Nakashima T, Ishiki K, Kuboki H, Hirano SI, Kumagai H, Yoshioka T, Ishizuka M, Takeuchi T, 2001. Synthesis and biological evaluation of cytogenin derivatives. Journal of Antibiotics, 54(3): 285-296 [本文引用:1]
[15]  Pairet L, Wrigley SK, Chetland I, Reynolds EE, Hayes MA, Holloway J, Ainsworth AM, Katzer W, Cheng XM, Hupe DJ, Charlton P, Doherty AM, 1995. Azaphilones with endothelin receptor binding activity produced by Penicillium sclerotiorum: taxonomy, fermentation, isolation, structure elucidation and biological activity. Journal of Antibiotics, 48(9): 913-923 [本文引用:1]
[16]  Reggelin M, Gerlach M, Vogt M, 1999. Metallated 2-alkenyl sulfoximines in asymmetric synthesis: regio-and stereoselective synthesis of highly substituted oxabicyclic ethers and studies towards the total syntheses of the euglobals G1 and G2 and arenaran A. European Journal of Organic Chemistry, 5: 1011-1031 [本文引用:1]
[17]  Saleem M, Ali MS, Hussain S, Jabbar A, Ashraf M, Lee YS, 2007. Marine natural products of fungal origin. Natural Product Reports, 24: 1142-1152 [本文引用:1]
[18]  Sun L, Li DL, Chen YC, Tao MH, Zhang WM, Dan FJ, 2011. Purification, identification and antitumor activities of secondary metabolites from marine fungus Eutypella scoparia FS26. Mycosystema, 30(2): 268-274 (in Chinese) [本文引用:1]
[19]  Wang X, Sena Filho JG, Hoover AR, King JB, Ellis TK, Powell DR, Cichewicz RH, 2010. Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. Journal of Natural Products, 73(5): 942-948 [本文引用:1]
[20]  Zelenkova NF, Vinokurova NG, Arinbasarov MU, 2003. Analysis of secondary metabolites of microscopic fungi of the genus Penicillium by chromatographic techniques. Applied Biochemistry and Microbiology, 39(1): 44-54 [本文引用:1]
[21]  Zhang L, Zhang QB, Chen YC, Li HH, Wang L, Zhang WM, 2013. Preliminary identification of 18 marine fungal strains from the South China Sea and screening of their fermentation products for cytotoxic and antibacterial activities. Journal of Tropical Oceanography, 32(3): 49-53 (in Chinese) [本文引用:1]
[22]  戴玉成, 杨祝良, 2008. 中国药用真菌名录及部分名称的修订. 菌物学报, 27: 801-824 [本文引用:1]
[23]  李丽, 杨锦飞, 袁相爱, 2005. 异香豆素类化合物的合成研究及新进展. 南京师范大学学报(工程技术版), 5(2): 64-27 [本文引用:1]
[24]  李庆欣, 史雪凤, 黄智, 田新朋, 王发左, 2013. 海洋真菌来源吲哚生物碱类化合物的结构和活性研究. 热带海洋学报, 32(1): 35-47 [本文引用:1]
[25]  孙利, 李冬利, 陈玉婵, 陶美华, 章卫民, 但飞君, 2011. 海洋真菌帚状弯孢聚壳FS26代谢产物的分离鉴定与抗肿瘤活性研究. 菌物学报, 30(2): 268-274 [本文引用:1]
[26]  张玲, 张庆波, 陈玉婵, 李浩华, 王磊, 章卫民, 2013. 18株南海海洋真菌的初步鉴定及其发酵产物的细胞毒活性和抗菌活性筛选. 热带海洋学报, 32(3): 47-51 [本文引用:1]

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