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化工学报  2014 

Al2O3@TiO2复合生物载体的制备及其BSA吸附特性

DOI: 10.3969/j.issn.0438-1157.2014.05.052, PP. 1920-1927

Keywords: 氧化铝,二氧化钛,生物载体,复合材料,蛋白质,吸附

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Abstract:

通过钛酸盐和氧化钛溶胶两种制备途径在氧化铝(Al2O3)支撑体外包覆介孔氧化钛(TiO2)层,分析了这两种途径制备的氧化钛表面结构与性质的差异及其对于BSA蛋白吸附性能的影响。以粒径分别为0.37、10.4和21.8mm的三种氧化铝支撑体作为基材,用XRD、Raman分析了两种路径制备的氧化钛晶型均为锐钛矿相;N2吸脱附分析其比表面积均在(100±10)m2·g-1,两者具有相似的介孔结构。FESEM分析发现钛酸钾溶胶制备的氧化钛的形貌受到支撑体孔径的影响。对于在牛血清蛋白(BSA)吸附实验中,钛酸钾溶胶法包覆的20mm粒径复合载体(SP20@K-TiO2)吸附量为22.18mg·g-1,高于相同条件下氧化钛溶胶制备的Al2O3@TiO2复合载体。SP20@K-TiO2中TiO2吸附量为150.88mg·g-1,相比于TiO2粉体,复合载体中TiO2对BSA蛋白吸附的性能得到提升。

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