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化工学报  2015 

离子液体中采用AGETATRP法制备MCC-g-PGMA

DOI: 10.11949/j.issn.0438-1157.20141846, PP. 365-369

Keywords: 离子液体,甲基丙烯酸缩水甘油酯,AGET,ATRP,微晶纤维素,分子合成,聚合物

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Abstract:

在氯化1-烯丙基-3-甲基咪唑([AMIM]Cl)离子液体中,采用AGETATRP技术,以VC为还原剂、CuBr2/乙二胺为催化体系,成功制备了微晶纤维素接枝聚甲基丙烯酸缩水甘油酯(MCC-g-PGMA)分子。研究表明:[AMIM]Cl对微晶纤维素有较好的溶解性,最佳反应条件为GMA/乙二胺/CuBr2/VC摩尔比为100:4:1:1,反应温度25℃,反应时间4h,接枝效率可达54.56%,分子量分布较窄为1.48。通过FT-IR、TEM和SEM测试表明:成功合成了MCC-g-PGMA接枝共聚物分子,PGMA接枝微晶纤维素后表面形态变得粗糙,接枝共聚物在丙酮溶液中可自组装成150~200nm的球形结构,在药物载体领域具有良好的应用潜能。

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