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OALib Journal期刊
ISSN: 2333-9721
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乙醛和不饱和三氟甲基酮不对称Aldol反应合成光学活性的β-三氟甲基-β-羟基-δ-戊内酯有机化学
DOI: 10.6023/cjoc201402028, PP. 1399-1406
Keywords: δ-戊内酯,不对称Aldol反应,碘内酯化,脱碘反应
Abstract:
以手性伯胺为催化剂催化共轭不饱和三氟甲基酮与乙醛的不对称反应为关键步骤，合成了光学活性的β-三氟甲基-β-羟基-δ-戊内酯.合成过程中包含乙醛和共轭不饱和三氟甲基酮的不对称Aldol反应、氧化反应、碘内酯化以及脱碘反应.
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