OALib Journal期刊
芳甲叉双噁唑啉-铜络合物催化三氟甲基丙酮酸酯与吲哚的傅-克烷基化反应研究有机化学
DOI: 10.6023/cjoc201505013
Keywords: 三氟甲基 ,傅-克烷基化 ,吲哚 ,双噁唑啉
Abstract:
报道了芳甲叉双噁唑啉-铜络合物催化三氟甲基丙酮酸酯对吲哚的傅-克烷基化反应,探讨了配体结构、溶剂、温度等因素对反应的影响.研究表明,反应表现出高活性和中等程度以上的对映选择性,吲哚环上取代基对催化反应有重要的影响.提供了一种合成含手性三氟甲基季碳吲哚化合物的新方法.
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