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OALib Journal期刊
ISSN: 2333-9721
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溴呋啶及其类似物的合成新方法研究有机化学
DOI: 10.6023/cjoc201410034, PP. 910-916
Keywords: 嗅呋啶,偕二溴代烯烃,脱溴反应
Abstract:
以5-甲酰基嘧啶核苷为原料,先经与四溴化碳缩合得5-(2,2-二溴乙烯基)嘧啶核苷类似物,然后在亚磷酸二乙酯和三乙胺的作用下发生立体选择性脱溴反应,高效合成了溴呋啶及其类似物.
| [1] | (a) Jordheim, L. P.; Durantel, D.; Zoulim, F.; Dumontet, C. Nat. Rev. Drug Discovery 2013, 12, 447.
|
| [2] | (b) Wainberg, M. A. Antiviral Res. 2009, 81, 1.
|
| [3] | (c) Jin, Y.-Y.; Xiao, Q.; Jv, Y. Chin. J. Org. Chem. 2009, 29, 44 (in Chinese).
|
| [4] | (靳玄烨, 肖强, 巨勇, 有机化学, 2009, 29, 44.)
|
| [5] | (d) Menéndez-Arias, L.; álvarez, M.; Pacheco, B. Curr. Opin. Virol. 2014, 8, 1.
|
| [6] | (a) Xia, Y.; Liu, Y.; Rocchi, P.; Wang, M.; Fan, Y.; Qu, F.; Iovanna, J. L.; Peng, L. Cancer Lett. 2012, 318, 145.
|
| [7] | (b) Wu, J.; Yu, W.; Fu, L.; He, W.; Wang, Y.; Chai, B.; Song, C.; Chang, J. Eur. J. Med. Chem. 2013, 63, 739.
|
| [8] | (c) Shirouzu, H.; Morita, H.; Tsukamoto, M. Tetrahedron 2014, 70, 3635.
|
| [9] | (a) Wainberg, M. A. Antiviral Res. 2009, 81, 1.
|
| [10] | (b) De Clercq, E. Rev. Med. Virol. 2009, 19, 287.
|
| [11] | (c) De Clercq, E. J. Med. Chem. 2010, 53, 1438.
|
| [12] | (d) De Clercq, E. Antiviral Res. 2010, 85, 19.
|
| [13] | Bleackley, R. C.; Jones, A. S.; Walker, R. T. Tetrahedron 1976, 32, 2795.
|
| [14] | Ashwell, M.; Jones, A. S.; Kumar, A.; Sayers, J. R.; Walker, R. T.; Sakuma, T.; de Clercq, E. Tetrahedron 1987, 43, 4601.
|
| [15] | Wang, C. J.; Xie, F.; Zhang, W. B. Chin. J. Org. Chem. 2008, 28, 503 (in Chinese).
|
| [16] | (王春娟, 谢芳, 张万斌, 有机化学, 2008, 28, 503.)
|
| [17] | Chelucci, G. Chem. Rev. 2012, 112, 1344 and references cited therein.
|
| [18] | (a) Hirao, T.; Masunaga, T.; Ohshiro, Y.; Agawa, T. J. Org. Chem. 1981, 46, 3745.
|
| [19] | (b) Abbas, S.; Hayes, C. J.; Worden, S. Tetrahedron Lett. 2000, 41, 3215.
|
| [20] | Fan, X. S.; Li, P. Y.; Li, K.; Zhang, X. Y.; Zhao, W. Chin. J. Org. Chem. 2014, 34, 999 (in Chinese).
|
| [21] | (范学森, 李培源, 李坤, 张新迎, 赵婉, 有机化学, 2014, 34, 999.)
|
| [22] | Corey, E. J.; Fuchs, P. L. Tetrahedron Lett. 1972, 13, 3769.
|
| [23] | (a) Wang, S. M.; Li, J.; Li, H. Y.; Liu, H. M.; Li, W. Chin. J. Org. Chem. 2008, 28, 120 (in Chinese).
|
| [24] | (王少敏, 李娟, 李华雨, 刘宏民, 李雯, 有机化学, 2008, 28, 120.)
|
| [25] | (b) Li, W.; Liu, H.-M.; You, Q.-D. Acta Chim. Sinica 2003, 61, 1516 (in Chinese).
|
| [26] | (李雯, 刘宏民, 尤启东, 化学学报, 2003, 61, 1516.)
|
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