1 Wheat P F. History and development of antimicrobial susceptibility testing methodology. J Antimicrob Chemother, 2001, 48: S1–S4？？
[2]
2 Bauer A W, Kirby W M, Sherris J C, et al. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol, 1966, 45: 493–496
[3]
3 CLSI. Performance standards for antimicrobial susceptibility testing. Twentieth. Informational Supplement. CLSI document M100-S20. Wayne, PA: Clinical and Laboratory Standard Institute, 2010
[4]
4 World Health Organization. Standardization of methods for conducting microbiology sensitivity tests. Second report of the expert committee on Antibiotics. WHO Technical Report Series, No. 210. WHO, Geneva, 1961
[5]
5 Gould I M. Towards a common susceptibility testing method? J Antimicrob Chemother, 2000, 45: 757–762
12 Shimkets L J, Dworkin M, Keller K H. A method for establishing stable concentration gradients in agar suitable for studying chemotaxis on a solid surface. Can J Microbiol, 1979, 25: 1460–1467？？
18 Bagel S, Hullen V, Wiedemann B, et al. Impact of gyrA and parC mutations on quinolone resistance, doubling time, and supercoiling degree of Escherichia coli. Antimicrob Agents Chemother, 1999, 43: 868–875
20 Brown D F. Determination of MICs by the E test. J Antimicrob Chemother, 1992, 29: 455？？
[19]
21 Hill G B, Schalkowsky S. Development and evaluation of the spiral gradient endpoint method for susceptibility testing of anaerobic gram-negative bacilli. Rev Infect Dis, 1990, 12: S200–S209？？
[20]
22 Cooper K E. Theory of antibiotic inhibition zones in agar media. Nature, 1995, 175: 510–511
[21]
23 Finn R K. Theory of agar diffusion methods for bioassay. Anal Chem, 1959, 31: 975–977？？
[22]
24 Awerbuch T E, Lustman L. A mathematical model for determining minimum inhibitory concentration (MIC) via diffusion assay. J Theory Biol, 1987, 129: 219–230？？
[23]
25 Ringertz S, Kronvall G. On the theory of the disk diffusion test. APMIS, 1988, 96: 484–490？？
[24]
26 Drugeon H B, Juvin M E, Caillon J, et al. Assessment of formulas for calculating critical concentration by the agar diffusion method. Antimicrob Agents Chemother, 1987, 31: 870–875
[25]
27 Anderson B. Improved susceptibility disk assay method employing an agar overlay technique. Antimicrob Agents Chemother, 1978, 14: 761–764
[26]
28 Bonev B, Hooper J, Parisot J. Principles of assessing bacterial susceptibility to antibiotics using the agar diffusion method. J Antimicrob Chemother, 2008, 61: 1295–1301？？
[27]
29 Andrews J M. The development of the BASA standsrdized method of disk diffusion testing. Antimicrob Agent Chemoth, 2001, 48: 29–42？？
[28]
30 Turnidge J, Paterson D L. Setting and revising antibacterial susceptibility breakpoints. Clin Microbiol Rev, 2007, 20: 391–408？？
32 Jorgensen J H, Crawford S A, Fulcher L C, et al. Multilaboratory Evaluation of disk diffusion antimicrobial susceptibility testing of Neisseria meningitidis isolates. J Clinical Microbiology, 2006, 44: 1744–1754？？
[31]
33 Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: measurement and potential uses of the mutant selection window. J Infect Dis, 2002, 185: 561–565？？
37 Cooper K E, Linton A H, Sehgal S N. The effect of inoculum size on inhibition zones in agar media using staphylococci and streptomycin. J Gen Microbiol, 1958, 18: 670–687
[36]
38 Firsov A A, Vostrov S N, Kononenko O V, et al. Prediction of the effects of inoculum size on the antimicrobial action of trovafloxacin and ciprofloxacin against Staphylococcus aureus and Escherichia coli in an in vitro dynamic model. Antimicrob Agents Chemoth, 1999, 43: 498–502
[37]
39 杨纪珂, 齐翔林, 陈霖. 生物数学概论. 北京: 科学出版社, 1982. 640–722
[38]
16 Liu Y Q, Zhang Y Z, Gao P J. Novel Concentration-Killing Curve method for estimation of bactericidal potency of antibiotics in an in vitro dynamic model. Antimicrob Agents Chemother, 2004, 48: 3884–3891？？
