69 Dahia C L, Rao A J. Regulation of FSH receptor, PKIbeta, IL-6 and calcium mobilization: Possible mediators of differential action of FSH. Mol Cell Endocrinol, 2006, 247: 73-81
[2]
70 Heckert L, Griswold M D. Expression of the FSH receptor in the testis. Recent Prog Horm Res, 1993, 48: 61-77
[3]
71 Li M W, Mruk D D, Cheng C Y. Mitogen-activated protein kinases in male reproductive function. Trends Mol Med, 2009, 15: 159-168
[4]
72 Gnessi L, Emidi A, Jannini E A, et al. Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action. J Cell Biol, 1995, 131: 1105-1121
[5]
73 Basciani S, Mariani S, Spera G, et al. Role of platelet-derived growth factors in the testis. Endocr Rev, 2010, 31: 916-939
[6]
74 Szczepny A, Hime G R, Loveland K L. Expression of hedgehog signalling components in adult mouse testis. Dev Dyn, 2006, 235: 3063-3070
[7]
75 Bitgood M J, Shen L, McMahon A P. Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr Biol, 1996, 6: 298-304
[8]
76 Golestaneh N, Beauchamp E, Fallen S, et al. Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells. Reproduction, 2009, 138: 151-162
[9]
77 Tanwar P S, Kaneko-Tarui T, Zhang L, et al. Constitutive WNT/beta- catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis. Biol Reprod, 2010, 82: 422-432
[10]
78 Ma P, Wang H, Guo R, et al. Stage-dependent Dishevelled-1 expression during mouse spermatogenesis suggests a role in regulating spermatid morphological changes. Mol Reprod Dev, 2006, 73: 774-783
[11]
79 Hacker A, Capel B, Goodfellow P, et al. Expression of Sry, the mouse sex determining gene. Development, 1995, 121: 1603-1614
[12]
80 De Cesare D, Fimia G M, Sassone-Corsi P. CREM, a master-switch of the transcriptional cascade in male germ cells. J Endocrinol Invest, 2000, 23: 592-596
[13]
81 Blendy J A, Kaestner K H, Weinbauer G F, et al. Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature, 1996, 380: 162-165
[14]
1 McCarrey J R, O''Brien D A, Skinner M K. Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries. J Androl, 1999, 20: 635-639
[15]
2 Su A I, Cooke M P, Ching K A, et al. Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci USA, 2002, 99: 4465-4470
[16]
3 Tanaka K, Tamura H, Tanaka H, et al. Spermatogonia-dependent expression of testicular genes in mice. Dev Biol, 2002, 246: 466-479
[17]
4 Rockett J C, Christopher Luft J, Brian Garges J, et al. Development of a 950-gene DNA array for examining gene expression patterns in mouse testis. Genome Biol, 2001, 2: RESEARCH0014
[18]
5 Sha J, Zhou Z, Li J, et al. Identification of testis development and spermatogenesis-related genes in human and mouse testes using cDNA arrays. Mol Hum Reprod, 2002, 8: 511-517
[19]
6 Pang A L, Taylor H C, Johnson W, et al. Identification of differentially expressed genes in mouse spermatogenesis. J Androl, 2003, 24: 899-911
[20]
7 Pang A L, Johnson W, Ravindranath N, et al. Expression profiling of purified male germ cells: stage-specific expression patterns related to meiosis and postmeiotic development. Physiol Genomics, 2006, 24: 75-85
[21]
8 Yu Z, Guo R, Ge Y, et al. Gene expression profiles in different stages of mouse spermatogenic cells during spermatogenesis. Biol Reprod, 2003, 69: 37-47
[22]
9 Guo R, Yu Z, Guan J, et al. Stage-specific and tissue-specific expression characteristics of differentially expressed genes during mouse spermatogenesis. Mol Reprod Dev, 2004, 67: 264-272
[23]
10 Clemente E J, Furlong R A, Loveland K L, et al. Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis. Mamm Genome, 2006, 17: 956-975
[24]
11 Schultz N, Hamra F K, Garbers D L. A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets. Proc Natl Acad Sci USA, 2003, 100: 12201-12206
[25]
12 Shima J E, McLean D J, McCarrey J R, et al. The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod, 2004, 71: 319-330
[26]
13 O''Shaughnessy P J, Fleming L, Baker P J, et al. Identification of developmentally regulated genes in the somatic cells of the mouse testis using serial analysis of gene expression. Biol Reprod, 2003, 69: 797-808
[27]
14 Wu S M, Baxendale V, Chen Y, et al. Analysis of mouse germ-cell transcriptome at different stages of spermatogenesis by SAGE: Biological significance. Genomics, 2004, 84: 971-981
[28]
15 Yao J, Chiba T, Sakai J, et al. Mouse testis transcriptome revealed using serial analysis of gene expression. Mamm Genome, 2004, 15: 433-451
[29]
16 Almstrup K. Analysis of cell-type-specific gene expression during mouse spermatogenesis. Biol Reprod, 2004, 70: 1751-1761
[30]
17 Ellis P J, Furlong R A, Wilson A, et al. Modulation of the mouse testis transcriptome during postnatal development and in selected models of male infertility. Mol Hum Reprod, 2004, 10: 271-281
[31]
18 Divina P, Vlcek C, Strnad P, et al. Global transcriptome analysis of the C57BL/6J mouse testis by SAGE: evidence for nonrandom gene order. BMC Genomics, 2005, 6: 29
[32]
19 Chan W Y, Lee T L, Wu S M, et al. Transcriptome analyses of male germ cells with serial analysis of gene expression (SAGE). Mol Cell Endocrinol, 2006, 250: 8-19
[33]
20 Lee T L, Cheung H H, Claus J, et al. GermSAGE: a comprehensive SAGE database for transcript discovery on male germ cell development. Nucleic Acids Res, 2009, 37: D891-897
[34]
21 Ike A, Tokuhiro K, Hirose M, et al. Comprehensive analysis of gene expression in testes producing haploid germ cells using DNA microarray analysis. Int J Androl, 2007, 30: 462-475
[35]
22 Xiao P, Tang A, Yu Z, et al. Gene expression profile of 2058 spermatogenesis-related genes in mice. Biol Pharm Bull, 2008, 31: 201-206
[36]
23 Waldman Ben-Asher H, Shahar I, Yitzchak A, et al. Expression and chromosomal organization of mouse meiotic genes. Mol Reprod Dev, 2010, 77: 241-248
[37]
24 Mortazavi A, Williams B A, McCue K, et al. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods, 2008, 5: 621-628
[38]
25 Wang Z, Gerstein M, Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet, 2009, 10: 57-63
[39]
26 Cui P, Lin Q, Ding F, et al. A comparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing. Genomics, 2010, 96: 259-265
[40]
27 Cui P, Lin Q, Xin C, et al. Hydroxyurea-induced global transcriptional suppression in mouse ES cells. Carcinogenesis, 2010, 31: 1661-1668
[41]
28 Gentleman R C, Carey V J, Bates D M, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol, 2004, 5: R80
[42]
29 Ashburner M, Ball C A, Blake J A, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet, 2000, 25: 25-29
[43]
30 Ye J, Fang L, Zheng H, et al. WEGO: a web tool for plotting GO annotations. Nucleic Acids Res, 2006, 34: W293-297
[44]
31 Wang L, Feng Z, Wang X, et al. DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics, 2010, 26: 136-138
[45]
32 Ogata H, Goto S, Sato K, et al. KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res, 1999, 27: 29-34
[46]
33 Kanehisa M, Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res, 2000, 28: 27-30
[47]
34 Kanehisa M, Goto S, Hattori M, et al. From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res, 2006, 34: D354-357
[48]
35 Kanehisa M, Goto S, Furumichi M, et al. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res, 2010, 38: D355-360
[49]
36 Dahlquist K D, Salomonis N, Vranizan K, et al. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet, 2002, 31: 19-20
[50]
37 Yeh J R, Nagano M C. Spermatogonial stem cell biomarkers: improved outcomes of spermatogonial transplantation in male fertility restoration? Expert Rev Mol Diagn, 2009, 9: 109-114
[51]
38 Kubota H, Avarbock M R, Brinster R L. Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells. Proc Natl Acad Sci USA, 2003, 100: 6487-6492
[52]
39 Phillips B T, Gassei K, Orwig K E. Spermatogonial stem cell regulation and spermatogenesis. Philos Trans R Soc Lond B Biol Sci, 2010, 365: 1663-1678
[53]
40 Suter L, Koch E, Bechter R, et al. Three-parameter flow cytometric analysis of rat spermatogenesis. Cytometry, 1997, 27: 161-168
[54]
41 Franke F E, Pauls K, Rey R, et al. Differentiation markers of Sertoli cells and germ cells in fetal and early postnatal human testis. Anat Embryol (Berl), 2004, 209: 169-177
[55]
42 O''Shaughnessy P J, Hu L, Baker P J. Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells. Reproduction, 2008, 135: 839-850
[56]
43 Haider S G. Cell biology of Leydig cells in the testis. Int Rev Cytol, 2004, 233: 181-241
[57]
44 O''Shaughnessy P J, Willerton L, Baker P J. Changes in Leydig cell gene expression during development in the mouse. Biol Reprod, 2002, 66: 966-975
[58]
45 Zhang F P, Pakarainen T, Zhu F, et al. Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice. Endocrinology, 2004, 145: 1453-1463
[59]
46 Kanamori M, Konno H, Osato N, et al. A genome-wide and nonredundant mouse transcription factor database. Biochem Biophys Res Commun, 2004, 322: 787-793
[60]
47 Ravasi T, Suzuki H, Cannistraci C V, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 2010, 140: 744-752
[61]
48 Zhou Q, Griswold M D. Regulation of spermatogonia. StemBook. Cambridge (MA): Harvard Stem Cell Institute, 2008
[62]
49 Sekido R. SRY: A transcriptional activator of mammalian testis determination. Int J Biochem Cell Biol, 2010, 42: 417-420
[63]
50 Barrionuevo F, Scherer G. SOX E genes: SOX9 and SOX8 in mammalian testis development. Int J Biochem Cell Biol, 2010, 42: 433-436
[64]
51 Tanaka H, Baba T. Gene expression in spermiogenesis. Cell Mol Life Sci, 2005, 62: 344-354
[65]
52 Meistrich M L, Mohapatra B, Shirley C R, et al. Roles of transition nuclear proteins in spermiogenesis. Chromosoma, 2003, 111: 483-488
[66]
53 Nayernia K, Adham I M, Burkhardt-Gottges E, et al. Asthenozoo- spermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene. Mol Cell Biol, 2002, 22: 3046-3052
[67]
54 Anway M D, Ravindranath N, Dym M, et al. Identification of a murine testis complementary DNA encoding a homolog to human A-kinase anchoring protein-associated sperm protein. Biol Reprod, 2002, 66: 1755-1761
[68]
55 Kierszenbaum A L, Tres L L. Structural and transcriptional features of the mouse spermatid genome. J Cell Biol, 1975, 65: 258-270
[69]
56 Heidaran M A, Kistler W S. Transcriptional and translational control of the message for transition protein 1, a major chromosomal protein of mammalian spermatids. J Biol Chem, 1987, 262: 13309-13315
[70]
57 Kleene K C. Poly(A) shortening accompanies the activation of translation of five mRNAs during spermiogenesis in the mouse. Development, 1989, 106: 367-373
[71]
58 Kleene K C, Bagarova J. Comparative genomics reveals gene-specific and shared regulatory sequences in the spermatid-expressed mammalian Odf1, Prm1, Prm2, Tnp1, and Tnp2 genes. Genomics, 2008, 92: 101-106
[72]
59 Sozubir S, Barber T, Wang Y, et al. Loss of Insl3: a potential predisposing factor for testicular torsion. J Urol, 2010, 183: 2373-2379
[73]
60 Nakamura N, Mori C, Eddy E M. Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5. Biol Reprod, 2010, 82: 504-515
[74]
61 Valentin M, Balvers M, Pusch W, et al. Structure and expression of the mouse gene encoding the endozepine-like peptide from haploid male germ cells. Eur J Biochem, 2000, 267: 5438-5449
[75]
62 Selvaraj V, Asano A, Page J L, et al. Mice lacking FABP9/PERF15 develop sperm head abnormalities but are fertile. Dev Biol, 2010, 348: 177-189
[76]
63 Dakhova O, O''Day D, Kinet N, et al. Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production. Endocrinology, 2009, 150: 404-412
[77]
64 Choi H S, Lee S H, Kim H, et al. Germ cell-specific gene 1 targets testis-specific poly(A) polymerase to the endoplasmic reticulum through protein-protein interactions. FEBS Lett, 2008, 582: 1203-1209
[78]
65 Bellve A R, Millette C F, Bhatnagar Y M, et al. Dissociation of the mouse testis and characterization of isolated spermatogenic cells. J Histochem Cytochem, 1977, 25: 480-494
[79]
66 Tegelenbosch R A, de Rooij D G. A quantitative study of spermatogonial multiplication and stem cell renewal in the C3H/101 F1 hybrid mouse. Mutat Res, 1993, 290: 193-200
[80]
67 Gassei K, Ehmcke J, Wood M A, et al. Immature rat seminiferous tubules reconstructed in vitro express markers of Sertoli cell maturation after xenografting into nude mouse hosts. Mol Hum Reprod, 2010, 16: 97-110
[81]
68 Steger K, Rey R, Louis F, et al. Reversion of the differentiated phenotype and maturation block in Sertoli cells in pathological human testis. Hum Reprod, 1999, 14: 136-143
