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miRNA在冠心病诊断和治疗中的研究进展

DOI: 10.1360/N052014-00241, PP. 748-754

Keywords: miRNA,冠心病,生物标记物,miRNA干扰

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Abstract:

miRNA是一类长度为18~22nt的非编码小RNA,可通过影响靶mRNA的翻译,对靶基因表达进行调控.最新研究表明,miRNA在冠心病的发生发展中起重要的调控作用,本文将对与冠心病密切联系的miRNA相关研究及miRNA干扰技术在冠心病治疗方面的研究进展进行综述,以探讨miRNA在冠心病等疾病诊断和治疗的应用前景.

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