1 Newschaffer C J, Croen L A, Daniels J, et al. The epidemiology of autism spectrum disorders. Annu Rev Public Health, 2007, 28: 235-258
[2]
2 Baird G, Simonoff E, Pickles A, et al. Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet, 2006, 368: 210-215
[3]
5 Battaglia A, Carey J C. Etiologic yield of autistic spectrum disorders: a prospective study. Am J Med Genet C Semin Med Genet, 2006, 142: 3-7
[4]
6 Schaefer G B, Lutz R E. Diagnostic yield in the clinical genetic evaluation of autism spectrum disorders. Genet Med, 2006, 8: 549-556
[5]
7 O''Roak B J, State M W. Autism genetics, strategies, challenges, and opportunities. Autism Res, 2008, 1: 4-17
[6]
8 Bailey A, Le Couteur A, Gottesman I, et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med, 1995, 25: 63-77
[7]
9 Fraga M F, Ballestar E, Paz M F, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA, 2005, 102: 10604-10609
[8]
10 Kumar R, Christian S. Genetics of autism spectrum disorders. Curr Neurol Neurosci Rep, 2009, 9: 188-197
[9]
11 Vorstman J A, Staal W G, van Daalen E, et al. Identification of novel autism candidate regions through analysis of reported cytogenetic abnormalities associated with autism. Mol Psychiatry, 2006, 11: 18-28
[10]
12 Patterson P H. Neuroscience. Maternal effects on schizophrenia risk. Science, 2007, 318: 576-577
[11]
13 Reichenberg A. Advancing paternal age and autism. Arch Gen Psychiatry, 2006, 63: 1026-1032
[12]
14 Dolen G. Correction of fragile X syndrome in mice. Neuron, 2007, 56: 955-962
[13]
15 Tabuchi K, Blundell J, Etherton M R, et al. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science, 2007, 318: 71-76
[14]
16 Kelleher R J, Bear M F. The autistic neuron: troubled translation. Cell, 2008, 135: 401-406
[15]
17 Eluvathingal T J, Behen M E, Chugani H T, et al. Cerebellar lesions in tuberous sclerosis complex: neurobehavioral and neuroimaging correlates. J Child Neurol, 2006, 21: 846-851
[16]
18 Zhou J, Blundell J, Ogawa S, et al. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci, 2009, 29: 1773-1783
[17]
19 Canitano R. Epilepsy in autism spectrum disorders. Eur Child Adolesc Psychiatry, 2007, 16: 61-66
[18]
20 Krey J F, Dolmetsch R E. Molecular mechanisms of autism: a possible role for Ca2+ signaling. Curr Opin Neurobiol, 2007, 17: 112-119
[19]
21 Herbert M R, Ziegler D A, Deutsch C K, et al. Brain asymmetries in autism and developmental language disorder: a nested whole-brain analysis. Brain, 2005, 128: 213-226
[20]
22 Dapretto M, Davies M S, Pfeifer J H, et al. Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders. Nature Neurosci, 2006, 9: 28-30
[21]
23 Courchesne E, Carper R, Akshoomoff N. Evidence of brain overgrowth in the first year of life in autism. Jama, 2003, 290: 337-344
[22]
24 Hogart A, Nagarajan R P, Patzel K A, et al. 15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders. Hum Mol Genet, 2007, 16: 691-703
[23]
25 Tierney E. Abnormalities of cholesterol metabolism in autism spectrum disorders. Am J Med Genet B Neuropsychiatr Genet, 2006, 141: 666-668
[24]
26 Kasari C, Freeman S, Paparella T. Joint attention and symbolic play in young children with autism: a randomized controlled intervention study. J Child Psychol Psychiatry, 2006, 47: 611-620
[25]
27 Sallows G O, Graupner T D. Intensive behavioral treatment for children with autism: four-year outcome and predictors. Am J Ment Retard, 2005, 110: 417-438
[26]
28 Smith T, Eikeseth S, Klevstrand M, et al. Intensive behavioural treatment for preschoolers with severe mental retardation and pervasive developmental disorder. Am J Ment Retard,1997, 102: 238-249
[27]
29 Jocelyn L J, Casiro O G, Beattie D, et al. Treatment of children with autism: a randomized controlled trial to evaluate a caregiver-based intervention program in community day-care centers. J Dev Behav Pediatr, 1998, 19: 326-334
[28]
30 Smith T, Groen A D, Wynn J W. Randomised trial of intensive early intervention for children with pervasive developmental disorder. Am J Ment Retard, 2000, 105: 269-285
[29]
31 Tebruegge M, Nandini V, Ritchie J. Does routine child health surveillance contribute to the early detection of children with pervasive developmental disorders? An epidemiological study in Kent, UK. BMC Pediatr, 2004, 4: 4-11
[30]
32 Johnson C P, Myers S M. Identification and evaluation of children with autism spectrum disorders. Pediatrics, 2007, 120: 1183-215
[31]
33 Rogers S J, Vismara L A. Evidence-based comprehensive treatments for early autism. J Clin Child Adolesc Psychol, 2008, 37: 8-38
[32]
3 Baron-Cohen S, Scott F J, Allison C, et al. Prevalence of autism-spectrum conditions: UK school-based population study. Br J Psychiatry, 2009, 194: 500-509
[33]
4 Wong V C N, Hui S L H. Epidemiological study of autism spectrum disorder in China. J Child Neurol, 2008, 23: 67-72
46 Todorov C, Freeston M H, Borgeat F. On the pharmacotherapy of obsessive-compulsive disorder: is a consensus possible? Can J Psychiatry, 2000, 45: 257-262
[47]
47 Durany N, Thome J. Neurotrophic factors and the pathophysiology of schizophrenic psychoses. Eur Psychiatry, 2004, 19: 326-337
49 Neves-Pereira M, Mundo E, Muglia P, et al. The brain-derived neurotrophic factor fene confers susceptibility to bipolar Disorder: evidence from a family-based association study. Am J Hum Genet, 2002, 71: 651-655