32 Kataoka M, Huang Z P, Wang D Z. Build a braveheart: the missing linc (RNA). Circ Res, 2013, 112: 1532-1534
[2]
33 Grote P, Wittler L, Hendrix D, et al. The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse. Dev Cell, 2013, 24: 206-214
[3]
34 Coppola A, Romito A, Borel C, et al. Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications. Stem Cell Res, 2014, 12: 323-337
[4]
35 Huang H N, Chen S Y, Hwang S M, et al. miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation. Stem Cell Res, 2014, 12: 338-353
[5]
36 Yao C X, Wei Q X, Zhang Y Y, et al. miR-200b targets GATA-4 during cell growth and differentiation. RNA Biol, 2013, 10: 465-480
[6]
37 Foronda D, De Navas L, Garaulet D, et al. Function and specificity of Hox genes. Int J Dev Biol, 2009, 53: 1404-1419
[7]
38 Nolte C, Jinks T, Wang X, et al.Shadow enhancers flanking the HoxB cluster direct dynamic Hox expression in early heart and endoderm development. Dev Biol, 2013, 383: 158-173
[8]
39 Makki N, Capecchi M R, Cardiovascular defects in a mouse model of HoxA1 syndrome. Hum Mol Genet, 2012, 21: 26-31
[9]
40 Behrens A N, Iacovino M, Lohr J L, et al. NKX2-5 mediates differential cardiac differentiation through interaction with HoxA10. Stem Cells Dev, 2013, 22: 2211-2220
[10]
1 Molitor A, Shen W H. The polycomb complex PRC1: composition and function in plants. J Genet Genomics, 2013, 40: 231-238
[11]
2 Su S, Zhang M, Li L, et al. Polycomb group genes as the key regulators in gene silencing. Wuhan Uni J Nat Sci, 2014, 19: 1-7
[12]
3 Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature, 2011, 469: 343-349
[13]
4 Luis N M, Morey L, Di Croce L, et al. Polycomb in stem cells: PRC1 branches out. Cell Stem Cell, 2012, 11: 16-21
[14]
5 van Wijk B, Moorman A F, van den Hoff M J. Role of bone morphogenetic proteins in cardiac differentiation. Cardiovasc Res, 2007, 74: 244-255
[15]
6 Clowes C, Boylan M G, Ridge L A, et al. The functional diversity of essential genes required for mammalian cardiac development. Genesis, 2014, 52: 713-737
[16]
7 Liang Q, De Windt L J, Witt S A, et al. The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J Biol Chem, 2001, 276: 30245-30253
[17]
8 Zhang H, Toyofuku T, Kamei J, et al. GATA-4 regulates cardiac morphogenesis through transactivation of the N-cadherin gene. Biochem Biophys Res Commun, 2003, 312: 1033-1038
[18]
9 Ma C X, Song Y L, Xiao L, et al.EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time-and dose-dependent manner. Cell Mol Life Sci, 2014, in press
[19]
10 Liang Q, Wiese R J, Bueno O F, et al. The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1-and 2-mediated phosphorylation of serine 105 in cardiomyocytes. Mol Cell Biol, 2001, 21: 7460-7469
[20]
11 Yanazume T, Hasegawa K, Morimoto T, et al. Cardiac p300 is involved in myocyte growth with decompensated heart failure. Mol Cell Biol, 2003, 23: 3593-3606
[21]
12 Carter D R, Buckle A D, Tanaka K, et al. Art27 interacts with GATA4, FOG2 and NKX2.5 and is a novel co-repressor of cardiac genes. PLoS One, 2014, 9: e95253
[22]
13 Liang Q, Molkentin J D. Divergent signaling pathways converge on GATA4 to regulate cardiac hypertrophic gene expression. J Mol Cell Cardiol, 2002, 34: 611-616
15 Hoffmann A D, Yang X H, Burnicka-Turek O, et al. Foxf genes integrate Tbx5 and hedgehog pathways in the second heart field for cardiac septation. PLoS Genet, 2014, 10: e1004604
[25]
16 Baban A, Postma A V, Marini M, et al. Identification of Tbx5 mutations in a series of 94 patients with Tetralogy of Fallot. Am J Med Genet A, 2014, 164: 3100-3107
[26]
17 Singh R, Horsthuis T, Farin H F, et al. Tbx20 interacts with smads to confine Tbx2 expression to the atrioventricular canal. Circ Res, 2009, 105: 442-452
[27]
18 Voronova A, Al M A, Fischer A, et al. Gli2 and MEF2C activate each other''s expression and function synergistically during cardiomyogenesis in vitro. Nucleic Acids Res, 2012, 40: 3329-3347
[28]
19 Morin S, Charron F, Robitaille L, et al. GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J, 2000, 19: 2046-2055
[29]
20 Vincentz J W, Barnes R M, Firulli A B. HAND factors as regulators of cardiac morphogenesis and implications for congenital heart defects. Birth Defects Res A Clin Mol Teratol, 2011, 91: 485-494
[30]
21 Barnes R M, Firulli B A, Conway S J, et al. Analysis of the HAND1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Dev Dyn, 2010, 239: 3086-3097
[31]
22 Kang X, Qi Y, Zuo Y, et al. SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell, 2010, 38: 191-201
[32]
23 Wang Q T. Epigenetic regulation of cardiac development and function by polycomb group and trithorax group proteins. Dev Dyn, 2012, 241: 1021-1033
[33]
24 Shirai M, Osugi T, Koga H, et al. The Polycomb-group gene Rae28 sustains NKX2.5/CSX expression and is essential for cardiac morphogenesis. J Clin Invest, 2002, 110: 177-184
[34]
25 He A, Ma Q, Cao J, et al. Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res, 2012, 110: 406-415
[35]
26 Delgado-Olguin P, Huang Y, Li X, et al. Epigenetic repression of cardiac progenitor gene expression by EZH2 is required for postnatal cardiac homeostasis. Nat Genet, 2012, 44: 343-347
[36]
27 He A, Shen X, Ma Q, et al. PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev, 2012, 26: 37-42
[37]
28 Zhang Z, Jones A, Sun C W, et al. PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming. Stem Cells, 2011, 29: 229-240
[38]
29 Klattenhoff C A, Scheuermann J C, Surface L E, et al. Braveheart, a long non-coding RNA required for cardiovascular lineage commitment. Cell, 2013, 152: 570-583
[39]
30 Chan S S, Shi X, Toyama A, et al. Mesp1 patterns mesoderm into cardiac, hematopoietic, or skeletal myogenic progenitors in a context-dependent manner. Cell Stem Cell, 2013, 12: 587-601
[40]
31 Quenet D, Dalal Y. A long non-coding RNA is required for targeting centromeric protein A to the human centromere. Elife, 2014, 3: e3254