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组织工程皮肤发展现状

DOI: 10.1360/N052014-00276, PP. 460-470

Keywords: 组织工程,组织工程皮肤,临床应用,生物材料,干细胞

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Abstract:

组织工程皮肤从概念提出至今技术发展迅速.本文对现有的组织工程皮肤进展展开论述,组织工程皮肤主要分3大类:由种子细胞和支架材料体外三维构建培养的组织工程皮肤、由细胞组成的组织工程化皮肤和由支架材料构成的组织工程化皮肤,根据其结构组成、形态或来源又分成2~3种,每种选1~3个代表具体描述.然后针对现有组织工程存在的再生修复性能不足、细胞来源受限、生产运输成本过高等技术问题进行分析讨论,同时就目前国家对该领域的管理办法进行了讨论和建议,并提出了组织工程皮肤的一些非移植性扩展应用.通过对组织工程皮肤领域技术成果的总结、技术问题与现有研究热点的讨论和未来前景的分析,希望能更好地促进该领域发展.

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