1 Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell, 2011, 146: 873-887
[2]
2 Lally D R, Gerstenblith A T, Regillo C D. Preferred therapies for neovascular age-related macular degeneration. Curr Opin Ophthalmol, 2012, 23: 182-188
[3]
3 Benedito R, Hellstr?m M. Notch as a hub for signaling in angiogenesis. Exp Cell Res, 2013, 319: 1281-1288
[4]
4 Kume T. Ligand-dependent Notch signaling in vascular formation. Adv Exp Med Biol, 2012, 727: 210-222
[5]
5 Dou G R, Wang L, Wang Y S, et al. Notch signaling in ocular vasculature development and diseases. Mol Med, 2012, 18: 47-55
[6]
6 Yan M, Callahan C A, Beyer J C, et al. Chronic DLL4 blockade induces vascular neoplasms. Nature, 2010, 463: E6-E7
[7]
7 Fortini M E, Bilder D. Endocytic regulation of Notch signaling. Curr Opin Genet Dev, 2009, 19: 323-328
[8]
8 Danhier F, Breton A L, Préat V. RGD-based strategies to target av b3 integrin in cancer therapy and diagnosis. Mol Pharm, 2012, 9: 2961-2973
[9]
9 Caswell P T, Vadrevu S, Norman J C. Integrins: masters and slaves of endocytic transport. Nat Rev Mol Cell Biol, 2009, 10: 843-853
[10]
10 Zhao X C, Dou G R, Wang L, et al. Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells. Neoplasia, 2013, 15: 815-825
[11]
11 Tian D M, Liang L, Zhao X C, et al. Endothelium-targeted Delta-like 1 promotes hematopoietic stem cell expansion ex vivo and engraftment in hematopoietic tissues in vivo. Stem Cell Res, 2013, 11: 693-706
[12]
12 Dou G R, Wang Y C, Hu X B, et al. RBP-J, the transcription factor downstream of Notch receptors, is essential for the maintenance of vascular homeostasis in adult mice. FASEB J, 2008 22: 1606-1617
[13]
13 Benedito R, Rocha S F, Woeste M, et al. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature, 2012, 484: 110-114
[14]
14 Hellstr?m M, Phng L K, Hofmann J J, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature, 2007, 445: 776-780
[15]
15 Zhang P, Yan X C, Chen Y, et al. Notch signaling in blood vessels: from morphogenesis to homeostasis. Sci China Life Sci, 2014, 57: 774-780
[16]
16 Ridgway J, Zhang G, Wu Y, et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature, 2006, 444: 1083-1087
[17]
17 Wu Y, Cain-Hom C, Choy L, et al. Therapeutic antibody targeting of individual Notch receptors. Nature, 2010, 464: 1052-1057
[18]
18 Noguera-Troise I, Daly C, Papadopoulos N J, et al. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature, 2006, 444: 1032-1037
[19]
19 Yan M. Therapeutic promise and challenges of targeting DLL4/NOTCH1. Vasc Cell, 2011, 3: 17
[20]
20 Scheppke L, Murphy E A, Zarpellon A, et al. Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood, 2012, 119: 2149-2158
[21]
21 Bentley K, Franco C A, Philippides A, et al. The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis. Nat Cell Biol, 2014, 16: 309-321
[22]
22 Zhang Y, Dong E. New insight into vascular homeostasis and injury-reconstruction. Sci China Life Sci, 2014, 57: 739-741