神经调节蛋白1在生殖发育中的研究进展
The Research Progress of Neuregulin 1 in the Reproductive Development

DOI: 10.12677/QRB.2015.23003, PP. 19-25

Keywords: 神经调节蛋白1，下丘脑，垂体，卵巢，生殖内分泌
Neuregulin 1, Hypothalamus, Pituitary, Ovarian, Reproductive Endocrine

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Abstract:

神经调节蛋白1 (NRG1)是神经调节蛋白家族成员之一，是NRG1基因选择性剪切编码的一种类表皮生长因子，具有促进神经元和肌细胞等多种细胞的增殖、分化及存活功能。NRG1对雌性动物的生殖、内分泌功能具有重要的调节功能。本文就NRG1在动物生殖内分泌中的研究进展，从下丘脑、垂体和卵巢三个水平进行综述。
Neuregulin 1 (NRG1) is one of Neuregulin proteins, a kind of epidermal growth factor encoded by the selective shear of NRG1 gene, which promotes proliferation, differentiation and survival of neurons, muscle and other cells. NRG 1 has an important regulating function on female reproductive endocrine. The research development of NRG1 in the field of animal reproductive endocrine is described on the hypothalamus, pituitary and ovarian in this paper.

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