In this paper functionalized multiwall carbon nanotubes (FMWCNT) were modified using atenolol as a class of drugs that were used in cardiovascular diseases containing reactable nitrogen, which could attach chemically to functionalized MWCNT. This product was characterized by Fourier transform infrared spectroscopy (FT-IR) and Raman spectroscopy. These spectrums proved the existence of nitrogen atoms of amide due to new functional group. The morphology were also determined by scanning electron microscopy (SEM) and showed that this product was synthesized in the nanometer dimension. Thermal gravimetery (TGA) analysis was also used to evaluate thermal properties.
References
[1]
Kalita, G., Adhikari, S., Aryal, H.R., Afre, R., Soga, T., Sharon, M. and Umeno, M. (2009) Functionalization of Multi-Walled Carbon Nanotubes (MWCNTs) with Nitrogen Plasma for Photovoltaic Device Application. Current Applied Physics, 351, 346-351. http://dx.doi.org/10.1016/j.cap.2008.03.007
[2]
Merkoci, A., Pumera, M., Llopis, X., Perez, B., Valle, M. and Alegret, S. (2005) New Materials for Electrochemical Sensing: Carbon Nanotubes. Trends in Analytical Chemistry, 24, 826-838. http://dx.doi.org/10.1016/j.trac.2005.03.019
[3]
Bianco, A., Kostarelos, K. and Prato, M. (2005) Applications of Carbon Nanotubes in Drug Delivery. Current Opinion in Chemical Biology, 9, 674-679. http://dx.doi.org/10.1016/j.cbpa.2005.10.005
[4]
Sedaghat, S. and Mehraji, M. (2013) Novel Hybrid of Silver Nono Particles Deposited on to the Different Carbon Substrates and Evaluation of Antibacterial Effects. Journal of Applied Science Engineering Technology, 3, 219-222.
[5]
Dettlaff-Weglikowska, U., Benoit, J.M., Chiu, P.W., Graupner, R., Lebedkin, S. and Roth, S. (2002) Chemical Functionalization of Single Walled Carbon Nanotubes. Current Applied Physics, 2, 497-501. http://dx.doi.org/10.1016/S1567-1739(02)00164-5
[6]
Agon, P., Goethals, P., Van Haver, D. and Kaufman, J.M. (1991) Permeability of The Blood-Brain Barrier for Atenolol Studied by Positron Emission Tomography. Journal of Pharmacy and Pharmacology, 43, 597-600. http://dx.doi.org/10.1111/j.2042-7158.1991.tb03545.x
[7]
Tahermansouri, H., Chobforosh, D. and Meskinfam, M. (2010) International Journal of Nano Dimension, 1, 153-159-158.
[8]
Shen, J., Huang, W. and Ye, M. (2007) Thermo-physical properties of epoxy nanocomposites reinforced with amino-functionalized multi-walled carbon nanotubes. Composite Part A, 38, 1331-1336. http://dx.doi.org/10.1016/j.compositesa.2006.10.012
[9]
Mickelson, E.T., Chiang, I.W., Zimmerman, J.L., Boul, P.J., Lozano, J., Liu, J., Smalley, R.E., Hauge, R.H. and Margrave, J.L. (1999) Solvation of Fluorinated Single-Wall Carbon Nanotubes in Alcohol Solvents. The Journal of Physical Chemistry B, 103, 4318-4322. http://dx.doi.org/10.1021/jp9845524
[10]
Boul, P.J., Liu, J., Mickelson, E.T., Huffman, C.B., Ericson, L.M., Chiang, I.W., Smith, K.A., Colbert, D.T., Hauge, R. H., Margrave, J.L. and Smalley, R.E. (1999) Reversible Sidewall Functionalization of Buckytubes. Chemical Physics Letters, 310, 367-372. http://dx.doi.org/10.1016/S0009-2614(99)00713-7
[11]
Saini, R.K., Chiang, I.W., Peng, H., Smalley, R.E., Billups, W.E., Hauge, R.H. and Margrave, J.L. (2003) Covalent Sidewall Functionalization of Single Wall Carbon Nanotubes. JACS, 125, 3617-3621. http://dx.doi.org/10.1021/ja021167q
[12]
Boul, P.J., Turner, K., Li, J., Pulikkathara, M.X., Dwivedi, R.C., Sosa, E.D., Lu, Y., Kuznetsov, O.V., Moloney, P., Wilkins, R., O’Rourke, M.J., Khabashesku, V.N., Arepalli, S. and Yowell, L. (2009) Single Wall Carbon Nanotube Response to Proton Radiation. The Journal of Physical Chemistry C, 113, 14467-14473. http://dx.doi.org/10.1021/jp808553u
[13]
Damian, C.-M. and Horia, A.M.P. (2010) Sci. Bull., Series B, 72.