In order to develop a novel
controlled-release material, we previously attempted to impregnate poly(L-lactide) (poly(L-LA)), poly(L-LA-ran-CL) (CL: ε-caprolactone) or poly(L-LA-ran-TEMC)
(TEMC: tetramethylene carbonate) with low boiling point, organic useful
compounds using supercritical carbon dioxide (scCO2) as the solvent.
In this work, the factors influencing impregnation of poly (L-LA) random copolymers
with useful compounds were investigated under scCO2 using the copolymers
previously used. The influence of temperature, pressure, and time on the
impregnation contents of the useful compounds on the copolymers was evaluated.
The polymer used, which is a base of this material, was poly(L-LA-ran-CL), poly(L-LA-ran-TEMC), or poly(L-LA-ran-DXO)
(DXO: 1,5-dioxepan-2-one). Statistical random copolymers of L-LA with CL, TEMC,
or DXO were synthesized using Sn(oct)2 as a catalyst at 150°C for
24 h without solvent. Preparation of the controlled-release materials was
carried out using essential bark oil from
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